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- Table of Contents
Facts about TNFAIP3-interacting protein 3.
NF-kappa-B inhibition is independent of TNFAIP3 binding. .
Human | |
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Gene Name: | TNIP3 |
Uniprot: | Q96KP6 |
Entrez: | 79931 |
Belongs to: |
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No superfamily |
A20; A20-binding inhibitor of NF-kappa-B activation 3; ABIN3; ABIN-3ABIN-3 beta; FLJ21162; LINDListeria induced; Listeria-induced gene protein; TNFAIP3 interacting protein 3; TNFAIP3-interacting protein 3 beta; TNFAIP3-interacting protein 3; TNIP3 beta
Mass (kDA):
38.943 kDA
Human | |
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Location: | 4q27 |
Sequence: | 4; NC_000004.12 (121131408..121227609, complement) |
Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL.
PMID: 11345586 by Staege H., et al. Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophages.
PMID: 17088249 by Wullaert A., et al. LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF- kappaB activation.