TMPRSS3 Antibodies

Transmembrane protease serine 3 (TMPRSS3)

Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity).

Activates ENaC (in vitro). .

Gene Information

Human
Gene Name:	TMPRSS3
Uniprot:	P57727
Entrez:	64699

Family

Belongs to:
peptidase S1 family

Alternative Names

DFNB10; DFNB8; EC 3.4.21; EC 3.4.21.-; gene similar to transmembrane serine protease10ECHOS1Serine protease TADG-12; serine protease TADG12; TADG12; transmembrane protease serine 3; transmembrane protease, serine 3; Tumor-associated differentially-expressed gene 12 protein

Molecular Weight

Mass (kDA):
49.405 kDA

Genomic Context

Human
Location:	21q22.3
Sequence:	21; NC_000021.9 (42371837..42396052, complement)

Tissue Specificity

Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Diseases

• Complete Hearing Loss
• Malignant Neoplasms
• Neoplasms
• Deafness Congenital
• Sensorineural Hearing Loss (disorder)
• Carcinoma
• Epithelial Ovarian Cancer
• Ovarian Neoplasm
• Prostatic Neoplasms
• Malignant Neoplasm Of Ovary
• Neoplasm Metastasis
• Adenocarcinoma

• Epilepsy
• Inflammation
• Pancreatic Neoplasm
• Malignant Neoplasm Of Pancreas
• Malignant Neoplasm Of Prostate
• Hearing Loss, Bilateral
• Genetic Diseases, Inborn

Pathways

• Transport
• Methylation
• Translation
• Dna Hypomethylation
• Proteolysis
• Interferon-gamma Production
• Dna Methylation

• Localization
• Secretion

PTMs

• Cleavage

• Glycosylation

• Methylation

Research Areas

• Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMPRSS3

Best Uses of the TMPRSS3 Marker by Boster Bio

The TMPRSS3 marker is a key indicator when analysing a boster. There are a few options. Boster Microplate Readers allow you to measure absorbance at approximately 450 nm. Boster Pipettes have the ability to dispense 0.5 ul up through 1 ml of aqueous solution. A multichannel pipette is a good choice if you plan to test large quantities of sample. Boster Bio will provide credit if you share your results and data with colleagues.

Boster Bio - TMPRSS3Marker

Boster Bio's Anti-TMPRSS3 anti-mouse antibody is suitable to be used in ELISA, Flow Cytometry and IHC-P as well as Western blotting. The antibody was effective against human, mouse, and rats samples. This kit includes everything you need for the experiments. Best Uses of the TMPRSS3 marker

The TMPRSS3 protein is a highly targeted protein that recognizes both human cells and the human genome. It consists only of Cpf1, a protein that is linked to a a catalyticdomain, and deaminase. This antibody recognizes human cells and allows for more accurate results in research. The antibody has been validated in several studies using Boster's Anti-TMPRSS3 Product.

Boster Bio: Best Uses Of The TM

The Anti-TMPRSS3 antibody from Boster Bio is tested in Flow Cytometry, Immunohistochemistry, and Western Blotting. It reacts with Human, Mouse, and Rat. Here are some examples of the most effective uses of this antibody. Below are some examples that illustrate the use of this antibody. All of these applications are available to scientists from all over the globe.

Boster Bio: AntiTMPRSS3 Marker

The Boster Bio. Anti-TMPRSS3 marker is a monoclonal antibody that detects TMPRSS3. This highly specific and highly active marker was developed in-house by Boster Bio. These monoclonal antibodies are fully validated in Western Blotting and Immunohistochemistry. Boster offers a range of conjugates to these antibodies that are suitable for a variety different applications.

The Boster Bio. Anti-TMPRSS3 marker is a monoclonal antibody which reacts with the protein TMPRSS3 in human, mouse, and rat tissues. It is not dangerous and does NOT contain BSA. The cost of the blocking peptide for injection is 1.0mg/ml. Pricing for the blocking peptide depends on the length of the immunogen.