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- Table of Contents
Facts about Transmembrane protein 98.
Human | |
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Gene Name: | TMEM98 |
Uniprot: | Q9Y2Y6 |
Entrez: | 26022 |
Belongs to: |
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TMEM98 family |
DKFZP564K1964; Protein TADA1; transmembrane protein 98
Mass (kDA):
24.611 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (32927910..32944315) |
Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina.
Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Secreted by exosomes through a non-classical pathway.
PMID: 25946230 by Fu W., et al. The Secreted Form of Transmembrane Protein 98 Promotes the Differentiation of T Helper 1 Cells.
PMID: 24852644 by Awadalla M.S., et al. Mutation in TMEM98 in a large white kindred with autosomal dominant nanophthalmos linked to 17p12-q12.