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- Table of Contents
Facts about Transmembrane protein 59-like.
Modulates the O-glycosylation and complex N- glycosylation steps occurring Throughout the Golgi maturation of APP.
Inhibits APP transfer to the cell surface and further shedding..
Human | |
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Gene Name: | TMEM59L |
Uniprot: | Q9UK28 |
Entrez: | 25789 |
Belongs to: |
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TMEM59 family |
BSMAPBrain-specific membrane-anchored protein; C19orf4; chromosome 19 open reading frame 4; transmembrane protein 59-like
Mass (kDA):
37.619 kDA
Human | |
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Location: | 19p13.11 |
Sequence: | 19; NC_000019.10 (18612870..18621040) |
Expressed preferentially at high level in the brain.
Golgi apparatus membrane; Single-pass type I membrane protein.
PMID: 10527841 by Elson G.C.A., et al. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12.
PMID: 20427278 by Ullrich S., et al. The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein.