Transmembrane protein 47 Antibodies

AND TMEM47 ELISA kits, Transmembrane protein 47 Proteins

Many biological assays use antibodies to detect Transmembrane protein 47, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transmembrane protein 47 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transmembrane protein 47 antibodies...

We validate the specificity of these antibodies to Transmembrane protein 47 by testing them on tissues known to express TMEM47 positively and negatively. Browse below to find the TMEM47 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEM47 Infographic by Boster Bio

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TMEM47 (NM_031442) Human Over-expression Lysate

Human

$628
Cat # LS083604
100 µg

TMEM47 Overview

Facts about Transmembrane protein 47.

TMEM47 3D structure. Source: alphafold

Transmembrane protein 47 (TMEM47)

Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly.

May govern F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity).

Gene Information

Human
Gene Name:	TMEM47
Uniprot:	Q9BQJ4
Entrez:	83604

Family

Belongs to:

TMEM47 family

Alternative Names

Transmembrane protein 47

Molecular Weight

Mass (kDA):
19.998 kDA

Genomic Context


Human

Location:	Xp21.1
Sequence:	X; NC_000023.11 (34627075..34657285, complement)

Tissue Specificity

Expressed in adult brain, fetal brain, cerebellum, heart, lung, prostate and thyroid.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell junction, adherens junction. Colocalizes with FYB1 at cell-cell contacts in podocytes.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEM47

References

PMID: 24603971 by Utami K.H., et al. Detection of chromosomal breakpoints in patients with developmental delay and speech disorders.

PMID: 25489052 by Myklebust L.M., et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects.