Tomoregulin-1 Antibodies

AND TMEFF1 ELISA kits, Tomoregulin-1 Proteins

Many biological assays use antibodies to detect Tomoregulin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tomoregulin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tomoregulin-1 antibodies...

We validate the specificity of these antibodies to Tomoregulin-1 by testing them on tissues known to express TMEFF1 positively and negatively. Browse below to find the TMEFF1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TMEFF1 Infographic by Boster Bio

All TMEFF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-TEFF1 TMEFF1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10268
100ul

TMEFF1 (NM_003692) Human Recombinant Protein

$813
Cat # PROTQ8IYR6
20 µg

TMEFF1 (NM_003692) Human Over-expression Lysate

Human

$628
Cat # LS008577
100 µg

TMEFF1 Overview

Facts about Tomoregulin-1.

TMEFF1 3D structure. Source: alphafold

Tomoregulin-1 (TMEFF1)

May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

Gene Information

Human
Gene Name:	TMEFF1
Uniprot:	Q8IYR6
Entrez:	8577

Family

Belongs to:

tomoregulin family

Alternative Names

C9orf2; H7365member 1; TMEFF1; Tomoregulin1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1

Molecular Weight

Mass (kDA):
40.934 kDA

Genomic Context


Human

Location:	9q31.1
Sequence:	9; NC_000009.12 (100473149..100577636)

Tissue Specificity

Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Nervousness
Glioma
Pituitary Diseases
Prostatic Neoplasms
Melanoma
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Brain
Carcinoma
Mammary Neoplasms

Malignant Neoplasm Of Prostate
Neuroblastoma
Severe Mental Retardation
Brain Neoplasms
Cardio-facio-cutaneous Syndrome

Pathways

Regeneration
Pathogenesis
Secretion
Cell Activation
Tissue Regeneration
Cell Differentiation
Pigmentation
Cell Growth

Limb Development
Localization

PTMs

Phosphorylation

Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMEFF1

References

PMID: 8752111 by Eib D.W., et al. A novel transmembrane protein with epidermal growth factor and follistatin domains expressed in the hypothalamo-hypophysial axis of Xenopus laevis.

PMID: 12743596 by Gery S., et al. TMEFF1 and brain tumors.