TM4SF1 Antibodies

AND TM4SF1 ELISA kits, TM4SF1 Proteins

Many biological assays use antibodies to detect TM4SF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TM4SF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TM4SF1 antibodies...

We validate the specificity of these antibodies to TM4SF1 by testing them on tissues known to express TM4SF1 positively and negatively. Browse below to find the TM4SF1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: M6PR

TM4SF1 Infographic by Boster Bio

All TM4SF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TM4SF1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A10368
0.1 mg

TM4SF1 Overview

Facts about Transmembrane 4 L6 family member 1.

TM4SF1 3D structure. Source: alphafold

Transmembrane 4 L6 family member 1 (TM4SF1)

Gene Information

Human
Gene Name:	TM4SF1
Uniprot:	P30408
Entrez:	4071

Family

Belongs to:

L6 tetraspanin family

Alternative Names

L6; M3s1; M3S1Tumor-associated antigen L6; Membrane component chromosome 3 surface marker 1; membrane component, chromosome 3, surface marker 1; TAAL6; TAAL6H-L6; TM4SF1; transmembrane 4 L six family member 1; transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1

Molecular Weight

Mass (kDA):
21.632 kDA

Genomic Context


Human

Location:	3q25.1
Sequence:	3; NC_000003.12 (149369022..149377781, complement)

Tissue Specificity

Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Neoplasm Metastasis
Cell Invasion
Lung Neoplasms
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Mammary Neoplasms
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Colorectal Neoplasms

Malignant Neoplasm Of Lung
Colorectal Cancer
Malignant Neoplasm Of Prostate
Tissue Adhesions
Pleural Neoplasms
Pleural Mesothelioma
Ovarian Neoplasm

Interacting Proteins

SDCBP2

Pathways

Cell Migration
Localization
Cell Activation
Glycosylation
Cell Motility
Cell Growth
T Cell Activation
Endocytosis
Regeneration
Transport
Cell Adhesion
Mitosis
Complement Activation

Cytokinesis
Endothelial Cell Migration
Drug Resistance
Keratinocyte Migration
Tissue Regeneration
Angiogenesis
Wound Healing

PTMs

Biotinylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TM4SF1

References

PMID: 1565644 by Marken J.S., et al. Cloning and expression of the tumor-associated antigen L6.

PMID: 7510285 by Marken J.S., et al. Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody.