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- Table of Contents
Facts about Transducin-like enhancer protein 4.
The impacts of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens growth and for SIX3 transcriptional auto-repression (By similarity).
Human | |
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Gene Name: | TLE4 |
Uniprot: | Q04727 |
Entrez: | 7091 |
Belongs to: |
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WD repeat Groucho/TLE family |
BCE1; BCE-1; E(spI); ESG4; homolog of Drosophila E(sp1); KIAA1261; Protein BCE-1; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer protein 4
Mass (kDA):
83.755 kDA
Human | |
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Location: | 9q21.31 |
Sequence: | 9; NC_000009.12 (79571773..79726882) |
In all tissues examined, mostly in brain, and muscle.
Nucleus.
PMID: 1303260 by Stifani S., et al. Human homologs of a Drosophila enhancer of split gene product define a novel family of nuclear proteins.
PMID: 18254933 by Jennings B.H., et al. The Groucho/TLE/Grg family of transcriptional co-repressors.