TIRAP Antibodies

AND TIRAP ELISA kits, TIRAP Proteins

Many biological assays use antibodies to detect TIRAP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIRAP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIRAP antibodies...

We validate the specificity of these antibodies to TIRAP by testing them on tissues known to express TIRAP positively and negatively. Browse below to find the TIRAP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIRAP Infographic by Boster Bio

All TIRAP Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Phospho-TIRAP (Y86) Antibody

Human, Mouse

ELISA, IHC

$380
Cat # A00950Y86
100ul

TIRAP (NM_001039661) Human Recombinant Protein

$813
Cat # PROTP58753
20 µg

Anti-TIRAP Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M00950-1
100 μl/vial

TIRAP (NM_001039661) Human Over-expression Lysate

Human

$628
Cat # LS114609
100 µg

TIRAP Overview

Facts about Toll/interleukin-1 receptor domain-containing adapter protein.

TIRAP 3D structure. Source: alphafold

Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP)

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune reaction. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response.

Positively regulates the production of TNF-alpha and interleukin-6. .

Gene Information

Human
Gene Name:	TIRAP
Uniprot:	P58753
Entrez:	114609

Family

Belongs to:

No superfamily

Alternative Names

adapter protein wyatt; Adaptor protein Wyatt; MAL; MyD88 adapter-like protein; MyD88-2; TIR domain-containing adapter protein; toll/interleukin-1 receptor domain-containing adapter protein; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; Toll-like receptor adaptor protein; wyatt

Molecular Weight

Mass (kDA):
23.883 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (126283087..126294933)

Tissue Specificity

Highly expressed in liver, kidney, spleen, skeletal muscle and heart. Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain.