TIAF1 Antibodies

AND TIAF1 ELISA kits, TIAF1 Proteins

Many biological assays use antibodies to detect TIAF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIAF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIAF1 antibodies...

We validate the specificity of these antibodies to TIAF1 by testing them on tissues known to express TIAF1 positively and negatively. Browse below to find the TIAF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIAF1 Infographic by Boster Bio

All TIAF1 Products

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Product

Figures

Specificity

Applications

Price

Human TIAF1 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO95411
Starting from 10ug

TIAF1 (NM_004740) Human Over-expression Lysate

Human

$628
Cat # LS009220
100 µg

TIAF1 Overview

Facts about TGFB1-induced anti-apoptotic factor 1.

TIAF1 3D structure. Source: alphafold

TGFB1-induced anti-apoptotic factor 1 (TIAF1)

Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1.
Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.

Gene Information

Human
Gene Name:	TIAF1
Uniprot:	O95411
Entrez:	9220

Family

Belongs to:

No superfamily

Alternative Names

12 kDa TGF-beta-1-induced antiapoptotic factor; KIAA0216; MAJN; molecule associated with Jak-3 N-terminal; MYO18A; MYSPDZ; SPR210; TGFB1-induced apoptotic factor 1; TGF-beta-1-induced antiapoptotic factor 1

Molecular Weight

Mass (kDA):
12.414 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (29073521..29075609, complement)

Tissue Specificity

Not detectable in normal kidney and liver. Up- regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Autoimmunity
Neoplasm Metastasis
Tumor Progression
Carcinoma, Papillary
Hydrocephalus
Carcinoma
Myeloid And Lymphoid Neoplasms With Fgfr1 Rearrangement
Malignant Neoplasms
Dental Plaque
Hirschsprung Disease
Papillary Thyroid Carcinoma
Plaque, Amyloid

Neuroblastoma
Cell Transformation, Neoplastic
Salivary Gland Diseases
Nerve Degeneration
Bisphosphonate-associated Osteonecrosis
Tissue Adhesions
Myeloproliferative Disease

Interacting Proteins

APP
Smad4

Pathways

Cell Death
Pathogenesis
Regulation Of Cell Death
Cell Migration
Response To Uv
Immune Response
Pigmentation

Innervation

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIAF1

References

PMID: 9918798 by Chang N.-S., et al. Cloning and characterization of a novel transforming growth factor- beta1-induced TIAF1 protein that inhibits tumor necrosis factor cytotoxicity.

PMID: 12829915 by van der Leij J., et al. High expression of TIAF-1 in chronic kidney and liver allograft rejection and in activated T-helper cells.