TIA1 Antibodies

AND TIA1 ELISA kits, TIA1 Proteins

Many biological assays use antibodies to detect TIA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TIA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TIA1 antibodies...

We validate the specificity of these antibodies to TIA1 by testing them on tissues known to express TIA1 positively and negatively. Browse below to find the TIA1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TIA1 Infographic by Boster Bio

All TIA1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Nucleolysin TIA-1 isoform p40 TIA1 Antibody Picoband®

1 Q&As

Human, Mouse

$370
Cat # PA2194
100 μg/vial

Anti-TIA1 (T-Cell-Restricted Intracellular Antigen-1) Monoclonal Antibody

5 Q&As

Human

Flow Cytometry, IF, WB

$486
Cat # M02763
100ug/vial

Anti-TIA1 Rabbit Monoclonal Antibody

Human, Mouse

IP, IF, IHC, ICC, WB

$370
Cat # M02763-1
100 μl

Anti-Nucleolysin TIA-1 isoform p40 TIA1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02763
100ul

Anti-Nucleolysin TIA-1 isoform p40 TIA1 Antibody

Human, Mouse

IP, IF, IHC, ICC, WB

$405
Cat # A02763-1
100ul

TIA1 (NM_022173) Human Over-expression Lysate

Human

$628
Cat # LS007072
100 µg

TIA1 Overview

Facts about Nucleolysin TIA-1 isoform p40.

TIA1 3D structure. Source: alphafold

Nucleolysin TIA-1 isoform p40 (TIA1)

Involved in other pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte cells.

May be involved in apoptosis. .

Gene Information

Human
Gene Name:	TIA1
Uniprot:	P31483
Entrez:	7072

Family

Belongs to:

No superfamily

Alternative Names

cytotoxic granule-associated RNA-binding protein; nucleolysin TIA-1 isoform p40; p40-TIA-1 (containing p15-TIA-1); p40-TIA-1; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA1 cytotoxic granule-associated RNA binding protein; TIA1 cytotoxic granule-associated RNA-binding protein; TIA-1

Molecular Weight

Mass (kDA):
42.963 kDA

Genomic Context


Human

Location:	2p13.3
Sequence:	2; NC_000002.12 (70209444..70248793, complement)

Subcellular Localizations

Cytoplasm, Stress granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.

Diseases

Lymphoma
Neoplasms
T-cell Lymphoma
Malignant Neoplasms
Diffuse Large B-cell Lymphoma
Ki-1+ Anaplastic Large Cell Lymphoma
Hodgkin Disease
Epstein-barr Virus Infections
Transient Ischemic Attack
Peripheral T-cell Lymphoma
Skin Neoplasms
B-cell Lymphomas

Inflammation
Leukemia
Malignant Paraganglionic Neoplasm
Lymphoproliferative Disorders
Virus Diseases
Lymphoma, T-cell, Cutaneous
Nose Neoplasms

Interacting Proteins

SNRNP70
SNRPA
SNRPC

Pathways

Translation
Pathogenesis
Immune Response
Localization
Cell Death
Cell Proliferation
Transport
Programmed Cell Death
Response To Oxidative Stress
Response To Stress
Dna Repair
Hypersensitivity
Inflammatory Response

Nuclear Import
Cell Growth
Angiogenesis
Rna Processing
Secretion
Cell Adhesion
Dosage Compensation

PTMs

Phosphorylation
Cleavage
Dephosphorylation

Biotinylation
Oxidation
Methylation

Ubiquitination

Research Areas

Adaptive Immunity
Apoptosis
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TIA1

References

PMID: 1934064 by Tian Q., et al. A polyadenylate binding protein localized to the granules of cytolytic lymphocytes induces DNA fragmentation in target cells.

PMID: 8176212 by Kawakami A., et al. Intron-exon organization and chromosomal localization of the human TIA-1 gene.