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- Table of Contents
Facts about Thrombospondin type-1 domain-containing protein 7A.
Human | |
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Gene Name: | THSD7A |
Uniprot: | Q9UPZ6 |
Entrez: | 221981 |
Belongs to: |
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No superfamily |
Gm837; KIAA0960; thrombospondin, type I, domain containing 7A; THSD7A
Mass (kDA):
185.363 kDA
Human | |
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Location: | 7p21.3 |
Sequence: | 7; NC_000007.14 (11370365..11832198, complement) |
Detected on kidney podocytes along the glomerular capillary wall (at protein level).
[Thrombospondin type-1 domain-containing protein 7A]: Cell membrane; Single-pass type I membrane protein. Cell projection. Detected on podocyte foot processes.; [Thrombospondin type-1 domain-containing protein 7A, soluble form]: Secreted. Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form.
PMID: 25394321 by Tomas N.M., et al. Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.
PMID: 22194972 by Kuo M.W., et al. Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis.