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Thrombospondin-1 Antibodies
AND THBS1 ELISA kits, Thrombospondin-1 Proteins
Many biological assays use antibodies to detect Thrombospondin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thrombospondin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thrombospondin-1 antibodies...
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THBS1 Infographic by Boster Bio
All THBS1 Products
Product
Figures
Specificity
Applications
Price
Anti-Thrombospondin/THBS1 Antibody Picoband®
1 Citations 6 Q&As
Human
WB
$370
Cat # PB9450
100 μg/vial
Cat # PB9450
100 μg/vial
Human THBS1/TSP1/Thrombospondin-1 ELISA Kit PicoKine®
2 Citations 13 Q&As
Human
ELISA
$499
Cat # EK0899
96 wells/kit, with removable strips.
Cat # EK0899
96 wells/kit, with removable strips.
Monkey
ELISA
$499
Cat # EK0899-PR
96 wells/kit, with removable strips.
Cat # EK0899-PR
96 wells/kit, with removable strips.
Anti-Thrombospondin/THBS1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, WB
$370
Cat # A00667-1
100 μg/vial
Cat # A00667-1
100 μg/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00667-2
100 μg/vial
Cat # A00667-2
100 μg/vial
THBS1 Overview
Facts about Thrombospondin-1.
Thrombospondin-1 (THBS1)
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin.
May play a role in dentinogenesis and/or upkeep of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties.
Gene Information
| Human | |
|---|---|
| Gene Name: | THBS1 |
| Uniprot: | P07996 |
| Entrez: | 7057 |
Family
| Belongs to: |
|---|
| thrombospondin family |
Alternative Names
THBS; THBS1; THBS-1; thrombospondin 1; Thrombospondin1; Thrombospondin-1; thrombospondin-1p180; TSP-1; TSP1thrombospondin-1; TSPTSP-1
Molecular Weight
Mass (kDA):
129.383 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q14 |
| Sequence: | 15; NC_000015.10 (39581079..39599466) |
Subcellular Localizations
Secreted. Cell surface. Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted by thrombin-activated platelets and binds to the cell surface in the presence of extracellular Ca(2+) (PubMed:6777381). Incorporated into the extracellular matrix of fibroblasts (PubMed:6341993). Also detected in the endoplasmic reticulum and sarcoplasmic reticulum where it plays a role in the ER stress response (By similarity).
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Tumor Angiogenesis
- Cell Transformation, Neoplastic
- Carcinogenesis
- Colorectal Cancer
- Colorectal Neoplasms
- Neoplasm Metastasis
- Adenoma
- Adenocarcinoma
- Malignant Neoplasm Of Stomach
- Stomach Neoplasms
Interacting Proteins
- CD36
- FN1
- HTRA1
- PCOLCE
- TGFB1
Pathways
- Methylation
- Angiogenesis
- Dna Methylation
- Pathogenesis
- Cell Growth
- Cell Proliferation
- Cell Adhesion
- Cell Migration
- Cell Cycle
- Mismatch Repair
- Dna Hypermethylation
- Gene Silencing
- Aging
PTMs
- Methylation
- Phosphorylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/THBS1
bosterbio.com/bosterbio-gene-info-cards/THBS1
References
PMID: 2430973 by Lawler J., et al. The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.
PMID: 2918029 by Hennessy S.W., et al. Complete thrombospondin mRNA sequence includes potential regulatory sites in the 3' untranslated region.
3 Publications of Boster Thrombospondin-1 Antibodies & ELISA Kits
- PubMed ID: 10.3389/fnins.2020.00737, Serum Exosomal Proteins F9 and TSP-1 as Potential Diagnostic Biomarkers for Newl...
- PubMed ID: 10.1080/14767058.2018.1441279, Maternal serum thrombospondin-1 is significantly altered in cases with establish...
- PubMed ID: 28831065, Reactive oxygen species%u2013mediated switching expression of MMP-3 in stromal f...
*More publications can be found for each product on its corresponding product page