Homeobox protein TGIF1 Antibodies

AND TGIF1 ELISA kits, Homeobox protein TGIF1 Proteins

Many biological assays use antibodies to detect Homeobox protein TGIF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein TGIF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein TGIF1 antibodies...

We validate the specificity of these antibodies to Homeobox protein TGIF1 by testing them on tissues known to express TGIF1 positively and negatively. Browse below to find the TGIF1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TGIF1 Infographic by Boster Bio

All TGIF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-TGIF TGIF1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04122
100ul

Anti-TGIF (TGIF1) Mouse Monoclonal Antibody [Clone ID: OTI1B12]

Human, Mouse, Rat

IHC, WB

$523
Cat # M04122
100 µl

Anti-TGIF/TGIF1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04122-1
100 μg/vial

TGIF (TGIF1) (NM_170695) Human Over-expression Lysate

Human

$628
Cat # LS007050
100 µg

TGIF1 Overview

Facts about Homeobox protein TGIF1.

TGIF1 3D structure. Source: alphafold

Homeobox protein TGIF1 (TGIF1)

Binds to a retinoid X receptor (RXR) reactive element in the mobile retinol-binding protein II promoter (CRBPII- RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element.

Active transcriptional corepressor of SMAD2. Links that the nodal signaling pathway into the bifurcation of the forebrain and the establishment of ventral midline structures.

Gene Information

Human
Gene Name:	TGIF1
Uniprot:	Q15583
Entrez:	7050

Family

Belongs to:

TALE/TGIF homeobox family

Alternative Names

5'-TG-3' interacting factor; homeobox protein TGIF; homeobox protein TGIF1; HPE4; MGC39747; TALE homeobox TG-interacting factor; TGFB-induced factor (TALE family homeobox); TGFB-induced factor homeobox 1; TGIF1; TGIFMGC5066,5'-TG-3'-interacting factor 1; transforming growth factor-beta-induced factor

Molecular Weight

Mass (kDA):
43.013 kDA

Genomic Context


Human

Location:	18p11.31
Sequence:	18; NC_000018.10 (3412009..3459978)

Subcellular Localizations

Nucleus.

Diseases

Holoprosencephaly
Malignant Neoplasms
Neoplasms
Leukemia
Carcinoma
Myopia
Severe Myopia
Congenital Anomaly Of Brain
Pituitary Diseases
Congenital Abnormality
Cleft Lip
Congenital Absence

Liver Carcinoma
Cell Invasion
Microphthalmos
Neoplasm Invasiveness
Myeloid Leukemia
Cyclocephaly
Liver Neoplasms

Interacting Proteins

AXIN1
Axin1
AXIN2
Axin2
CTBP2

LGALS8
MDFI
PML

Pathways

Localization
Pathogenesis
Methylation
Rna Interference
Cell Activation
Cellular Senescence
Brain Development
Lung Development
Regulation Of Gene Expression
Chondrocyte Differentiation
Spermatogenesis
Cell Cycle Arrest
Inflammatory Response

System Development
Cell Cycle
Histone Acetylation
Cell Differentiation
Gastrulation
Jnk Cascade
Macrophage Activation

PTMs

Phosphorylation

Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGIF1

References

PMID: 8537382 by Bertolino E., et al. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif.

PMID: 10764806 by Yang Y., et al. Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.