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- Table of Contents
Facts about Transforming growth factor beta receptor type 3.
Binds to TGF-beta.
Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors..
Human | |
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Gene Name: | TGFBR3 |
Uniprot: | Q03167 |
Entrez: | 7049 |
Belongs to: |
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No superfamily |
betaglycan proteoglycan; Betaglycan; BGCAN; TBRIII; TGF-beta receptor type 3; TGF-beta receptor type III; TGF-beta RIII; TGFbetaRIII; TGFBR3; TGF-bRIII; TGFR-3; Transforming growth factor beta receptor III; transforming growth factor beta receptor type 3; transforming growth factor, beta receptor III (betaglycan, 300kDa); transforming growth factor, beta receptor III
Mass (kDA):
93.499 kDA
Human | |
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Location: | 1p22.1 |
Sequence: | 1; NC_000001.11 (91680343..91906002, complement) |
Secreted. Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
PMID: 1333192 by Moren A., et al. Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors.
PMID: 10944857 by Zippert R., et al. Eleven single nucleotide polymorphisms and one triple nucleotide insertion of the human TGF-beta III receptor gene.