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TGFB1 Antibodies
AND TGFB1 ELISA kits, TGFB1 Proteins
Many biological assays use antibodies to detect TGFB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TGFB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TGFB1 antibodies...
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TGFB1 Infographic by Boster Bio
All TGFB1 Products
Product
Figures
Specificity
Applications
Price
Human TGF Beta 1 ELISA Kit PicoKine®
105 Citations 15 Q&As
Human
ELISA
$399
Cat # EK0513
96 wells/kit, with removable strips.
Cat # EK0513
96 wells/kit, with removable strips.
Rat TGF Beta 1 ELISA Kit PicoKine®
92 Citations 19 Q&As
Rat
ELISA
$499
Cat # EK0514
96 wells/kit, with removable strips.
Cat # EK0514
96 wells/kit, with removable strips.
Mouse TGF Beta 1 ELISA Kit PicoKine®
106 Citations 17 Q&As
Mouse
ELISA
$399
Cat # EK0515
96 wells/kit, with removable strips.
Cat # EK0515
96 wells/kit, with removable strips.
Canine
ELISA
$399
Cat # EK0513-CN
96 wells/kit, with removable strips.
Cat # EK0513-CN
96 wells/kit, with removable strips.
Bovine TGF Beta 1 ELISA Kit PicoKine®
1 Citations 10 Q&As
Bovine
ELISA
$399
Cat # EK0513-BV
96 wells/kit, with removable strips.
Cat # EK0513-BV
96 wells/kit, with removable strips.
Pig porcine TGF Beta 1 ELISA Kit PicoKine®
1 Citations 5 Q&As
Pig
ELISA
$399
Cat # EK0513-PO
96 wells/kit, with removable strips.
Cat # EK0513-PO
96 wells/kit, with removable strips.
Rabbit TGF Beta 1 ELISA Kit PicoKine®
1 Citations 11 Q&As
Rabbit
ELISA
$399
Cat # EK0513-RB
96 wells/kit, with removable strips.
Cat # EK0513-RB
96 wells/kit, with removable strips.
Monkey
ELISA
$399
Cat # EK0513-PR
96 wells/kit, with removable strips.
Cat # EK0513-PR
96 wells/kit, with removable strips.
Mouse TGF-beta 1 Recombinant Protein
1 Citations
SDS-PAGE, Denatured
$265
Cat # PROTP04202
Starting from 10ug
Cat # PROTP04202
Starting from 10ug
Human, Mouse, Rat
Flow Cytometry, IF, WB
$523
Cat # M00019-3
100 µl
Cat # M00019-3
100 µl
Mouse
Cell Culture
$77
Cat # PROTP04202-2
5ug,20ug,100ug
Cat # PROTP04202-2
5ug,20ug,100ug
Swine
Cell Culture
$154
Cat # PROTP07200
5ug,20ug
Cat # PROTP07200
5ug,20ug
Human
Cell Culture
$77
Cat # PROTP01137-10
5ug,20ug,100ug
Cat # PROTP01137-10
5ug,20ug,100ug
TGFB1 Overview
Facts about Transforming growth factor beta-1 proprotein.
Transforming growth factor beta-1 proprotein (TGFB1)
Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors.
It plays an important role in bone remodeling as it's a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in dedicated osteoblasts (By similarity). Stimulates sustained production of collagen through the activation of CREB3L1 by regulated intramembrane proteolysis (RIP) (PubMed:25310401).
Gene Information
| Human | |
|---|---|
| Gene Name: | TGFB1 |
| Uniprot: | P01137 |
| Entrez: | 7040 |
Family
| Belongs to: |
|---|
| TGF-beta family |
Alternative Names
CED; DPD1; LAP; TGFB; TGFB1; TGF-beta 1, 2, 3; TGFbeta; transforming growth factor, beta 1
Molecular Weight
Mass (kDA):
44.341 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (41330323..41353922, complement) |
Tissue Specificity
Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage.
Subcellular Localizations
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix.; [Transforming growth factor beta-1]: Secreted.
Diseases
- Fibrosis
- Malignant Neoplasms
- Neoplasms
- Inflammation
- Kidney Diseases
- Carcinoma
- Tissue Adhesions
- Hepatic Fibrosis
- Liver Cirrhosis
- Diabetic Nephropathy
- Diabetes Mellitus
- Hypertrophy
- Tumor Angiogenesis
Interacting Proteins
- APP
- DIP2A
- ENG
- FSTL1
- LRRC32
- MEOX2
- PSG1
- TGFBR1
- TGFBR2
- TGFBR3
Pathways
- Pathogenesis
- Cell Proliferation
- Secretion
- Wound Healing
- Cell Growth
- Angiogenesis
- Regeneration
- Cell Cycle
- Localization
- Excretion
- Cell Death
- Cell Adhesion
- Immune Response
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Dephosphorylation
- Acetylation
- Nitration
- Glycosylation
- Phosphorothioation
- Ubiquitination
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGFB1
bosterbio.com/bosterbio-gene-info-cards/TGFB1
References
PMID: 3470709 by Derynck R., et al. Intron-exon structure of the human transforming growth factor-beta precursor gene.
PMID: 3861940 by Derynck R., et al. Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.
351 Publications of Boster TGFB1 Antibodies & ELISA Kits
- PubMed ID: PMID:33042615, The role of Nrf2/PIWIL2/purine metabolism axis in controlling radiation-induced ...
- PubMed ID: PMID:26097528, 3,4-dihydroxyphenylethanol suppresses irradiation-induced pulmonary fibrosis in ...
- PubMed ID: PMID:25664038, Imbalances of Th17 and Treg cells and their respective cytokines in COPD patient...
- PubMed ID: PMID:25337218, Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of ra...
- PubMed ID: PMID:18776948, HSV-1 infection suppresses TGF-β1 and SMAD3 expression in human corneal epithel...
- PubMed ID: 10.5483/BMBRep.2007.40.2.180, Aldosterone Up-regulates Production of Plasminogen Activator Inhibitor-1 by Rena...
- PubMed ID: 10.4314/ajtcam.v11i5.3, Benefical Therapeutic Effect of Chinese Herbal Xinji′Erkang formula on Hyperte...
- PubMed ID: 10.4168/aair.2021.13.1.88, The Role of Macrophage Migration Inhibitory Factor (MIF) in Asthmatic Airway Rem...
- PubMed ID: 10.4161/rna.34345, MiR-663 inhibits radiation-induced bystander effects by targeting TGFB1 in a fee...
- PubMed ID: 10.3892/mmr.2020.11277, Activation of calcium‑sensing receptor‑mediated autophagy in high glucose‑...
- PubMed ID: 10.3892/mmr.2019.10694, Role of CCR7 on dendritic cell‑mediated immune tolerance in the airways of all...
- PubMed ID: 10.3892/mmr.2019.10330, Calcium‑sensing receptor promotes high glucose‑induced myocardial fibrosis v...
- PubMed ID: 10.3892/mmr.2017.7563, Pigment epithelium‑derived factor protects human glomerular mesangial cells fr...
- PubMed ID: 10.3892/mmr.2017.7424, Urotensin II enhances transforming growth factor‑β1 expression and secretion ...
- PubMed ID: 10.3892/mmr.2017.6402, Protective effects of oleanolic acid on oxidative stress and the expression of c...
- PubMed ID: 10.3892/mmr.2016.5735, Mechanism of tacrolimus-induced chronic renal fibrosis following transplantation...
- PubMed ID: 10.3892/mmr.2014.3051, Molecular responses of radiation-induced liver damage in rats
- PubMed ID: 10.3892/mmr.2014.2606, Tumor cell lysate induces the immunosuppression and apoptosis of mouse immunocyt...
- PubMed ID: 10.3892/etm.2021.10002, Clinical significance of serum transforming growth factor‑β1 and procollagen ...
- PubMed ID: 10.3892/etm.2018.6995, Thalidomide decreases high glucose‑induced extracellular matrix protein synthe...
- PubMed ID: 10.3892/etm.2017.4555, Efficacies of rosiglitazone and retinoin on bleomycin‑induced pulmonary fibros...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page