LEFTY2 Antibodies

AND LEFTY2 ELISA kits, LEFTY2 Proteins

Many biological assays use antibodies to detect LEFTY2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LEFTY2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LEFTY2 antibodies...

We validate the specificity of these antibodies to LEFTY2 by testing them on tissues known to express LEFTY2 positively and negatively. Browse below to find the LEFTY2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LEFTY2 Infographic by Boster Bio

All LEFTY2 Products

Product

Figures

Specificity

Applications

Price

Anti-LEFTY A LEFTY2 Monoclonal Antibody

3 Q&As

Human

ELISA, WB

$612
Cat # M06558
100ug

Anti-LEFTY2 Antibody

Human

$298
Cat # M06558-1
80 µl

Anti-LEFTY1 + LEFTY2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M06558-2
100 μl/vial

LEFTY2 Overview

Facts about Left-right determination factor 2.

LEFTY2 3D structure. Source: alphafold

Left-right determination factor 2 (LEFTY2)

Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.

Gene Information

Human
Gene Name:	LEFTY2
Uniprot:	O00292
Entrez:	7044

Family

Belongs to:

TGF-beta family

Alternative Names

Ebaf; Endometrial Bleeding-Associated Factor; LEFTA; Left-Right Determination Factor 2; Left-right determination factor A; Lefty-2; LEFTYA; Protein Lefty-2; Protein Lefty-A; TGFB4; TGF-beta 4; TGF-beta-4; Transforming Growth Factor Beta-4

Molecular Weight

Mass (kDA):
40.92 kDA

Genomic Context


Human

Location:	1q42.12
Sequence:	1; NC_000001.11 (225936598..225941492, complement)

Tissue Specificity

Mesenchymal cells of the endometrial stroma.

Subcellular Localizations

Secreted.

Diseases

Endometrial Polyp
Cyclocephaly
Congenital Heart Defects
Hemorrhage
Infertility
Neoplasms
Congenital Abnormality
Female Infertility
Immunologic Deficiency Syndromes
Situs Ambiguus
Teratoma
Teratocarcinoma

Autoimmunity
Pregnancy Complications
Atresia
Embryonal Carcinoma
Melanoma
Seminoma
Uterine Hemorrhage

Pathways

Gastrulation
Decidualization
Localization
Heart Looping
Embryo Implantation
Cell Cycle
Diestrus
Segmentation
Cell Development
Epithelial To Mesenchymal Transition
Axis Specification
Heart Morphogenesis
Transport

Neural Crest Cell Development
Neural Tube Closure
Stem Cell Differentiation
Nodal Signaling Pathway
Fertilization
Mesoderm Formation
Metestrus

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LEFTY2

References

PMID: 9153275 by Kothapalli R., et al. Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding.

PMID: 10053005 by Kosaki K., et al. Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.