TFR2 Antibodies

AND TFR2 ELISA kits, TFR2 Proteins

Many biological assays use antibodies to detect TFR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFR2 antibodies...

We validate the specificity of these antibodies to TFR2 by testing them on tissues known to express TFR2 positively and negatively. Browse below to find the TFR2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TFR2 Infographic by Boster Bio

All TFR2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Transferrin receptor protein 2 TfR2 Antibody

Human

IHC, WB

$405
Cat # A02353
100ul

Anti-Transferrin receptor protein 2 TFR2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02353-1
100ul

Anti-Transferrin Receptor 2 (TFR2) Mouse Monoclonal Antibody [Clone ID: OTI2B4]

Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M02353
100 µl

Anti-Transferrin Receptor 2 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M02353-1
100 μl/vial

Transferrin Receptor 2 (TFR2) (NM_003227) Human Over-expression Lysate

Human

$960
Cat # LS007036
100 µg

TFR2 Overview

Facts about Transferrin receptor protein 2.

TFR2 3D structure. Source: alphafold

Transferrin receptor protein 2 (TFR2)

Mediates cellular uptake of transferrin-bound iron at a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation.

Gene Information

Human
Gene Name:	TFR2
Uniprot:	Q9UP52
Entrez:	7036

Family

Belongs to:

peptidase M28 family

Alternative Names

HFE3; HFE3transferrin receptor protein 2; MGC126368; TfR2; TFRC2; transferrin receptor 2

Molecular Weight

Mass (kDA):
88.755 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (100620416..100641552, complement)

Tissue Specificity

Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.; [Isoform Beta]: Cytoplasm. Lacks the transmembrane domain. Probably intracellular.

Diseases

Hemochromatosis
Iron Overload
Hereditary Hemochromatosis
Anemia
Liver Carcinoma
Juvenile Hemochromatosis
Iron Metabolism Disorders
Malignant Neoplasms
Liver Cirrhosis
Iron Deficiency
Hereditary Diseases
Diabetes Mellitus
Leukemia

Neoplasms
Hepatitis
Hepatitis C
Liver Neoplasms
Hepatitis C, Chronic
Cardiomyopathies
Iron Deficiency Anemia

Pathways

Transport
Pathogenesis
Endocytosis
Localization
Cell Cycle
Secretion
Receptor-mediated Endocytosis
Cell Proliferation
Pigmentation
Inflammatory Response
Cell Growth
Electron Transport
Protein Maturation

V(d)j Recombination
Liver Development
Intestinal Absorption
Translation
Acute-phase Response
Liver Regeneration
Erythrocyte Maturation

PTMs

Phosphorylation

Biotinylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFR2

References

PMID: 10409623 by Kawabata H., et al. Molecular cloning of transferrin receptor 2: a new member of the transferrin receptor-like family.

PMID: 9799793 by Gloeckner G., et al. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.