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- Table of Contents
1 Citations 7 Q&As
Facts about Trefoil factor 3.
.
Human | |
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Gene Name: | TFF3 |
Uniprot: | Q07654 |
Entrez: | 7033 |
Belongs to: |
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No superfamily |
HITF, human intestinal trefoil factor10Intestinal trefoil factor; ITF; TFF3; TFI; trefoil factor 3 (intestinal)
Mass (kDA):
10.181 kDA
Human | |
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Location: | 21q22.3 |
Sequence: | 21; NC_000021.9 (42311667..42315596, complement) |
Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level).
Secreted, extracellular space, extracellular matrix. Cytoplasm.
PMID: 9070946 by Seib T., et al. The three human trefoil genes TFF1, TFF2, and TFF3 are located within a region of 55 kb on chromosome 21q22.3.
PMID: 10950923 by Berry A., et al. Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region.
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