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- Table of Contents
Facts about Transcription factor Dp-2.
The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis.
Human | |
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Gene Name: | TFDP2 |
Uniprot: | Q14188 |
Entrez: | 7029 |
Belongs to: |
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E2F/DP family |
DKFZp313O196; DP2Dp-2; E2F dimerization partner 2; FLJ39131; transcription factor Dp-2 (E2F dimerization partner 2); transcription factor Dp-2
Mass (kDA):
49.236 kDA
Human | |
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Location: | 3q23 |
Sequence: | 3; NC_000003.12 (141944428..142149544, complement) |
High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Nucleus.
PMID: 7739537 by Wu C.-L., et al. In vivo association of E2F and DP family proteins.
PMID: 7784053 by Zhang Y., et al. Cloning and characterization of human DP2, a novel dimerization partner of E2F.