TFCP2L1 Antibodies

AND TFCP2L1 ELISA kits, TFCP2L1 Proteins

Many biological assays use antibodies to detect TFCP2L1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFCP2L1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFCP2L1 antibodies...

We validate the specificity of these antibodies to TFCP2L1 by testing them on tissues known to express TFCP2L1 positively and negatively. Browse below to find the TFCP2L1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TFCP2L1 Infographic by Boster Bio

All TFCP2L1 Products

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Specificity

Applications

Price

Anti-TFCP2L1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A08278
0.1 mg

CRTR1 (TFCP2L1) (NM_014553) Human Over-expression Lysate

Human

$628
Cat # LS029842
100 µg

TFCP2L1 Overview

Facts about Transcription factor CP2-like protein 1.

TFCP2L1 3D structure. Source: alphafold

Transcription factor CP2-like protein 1 (TFCP2L1)

Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity).

Required for normal duct improvement in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity).

Gene Information

Human
Gene Name:	TFCP2L1
Uniprot:	Q9NZI6
Entrez:	29842

Family

Belongs to:

grh/CP2 family

Alternative Names

CRTR1; CRTR1CRTR-1; LBP9; LBP-9; LBP9CP2-related transcriptional repressor 1; TFCP2L1; transcription factor CP2-like 1; transcription factor CP2-like protein 1; Transcription factor LBP-9

Molecular Weight

Mass (kDA):
54.627 kDA

Genomic Context


Human

Location:	2q14.2
Sequence:	2; NC_000002.12 (121216587..121285210, complement)

Tissue Specificity

Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Thyroid Neoplasm
Neoplasm Metastasis
Malignant Neoplasm Of Kidney
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast
Neoplasm By Morphology
Kidney Neoplasm
Carcinoma, Papillary
Braf Np_004324.2:p.v600e
Goiter

Renal Cell Carcinoma
Cytoplasmic Accumulation
Mammary Neoplasms
Papillary Thyroid Carcinoma
Anaplasia
Lung Neoplasms
Primary Neoplasm

Pathways

Methylation
Gene Silencing
Cell Cycle
Protein Folding
Dedifferentiation
Localization
Transdifferentiation

Protein Oligomerization

PTMs

Cleavage

Sumoylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFCP2L1

References

PMID: 10644752 by Huang N., et al. Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.

PMID: 25215486 by Takashima Y., et al. Resetting transcription factor control circuitry toward ground-state pluripotency in human.