TESC Antibodies

AND TESC ELISA kits, TESC Proteins

Many biological assays use antibodies to detect TESC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TESC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TESC antibodies...

We validate the specificity of these antibodies to TESC by testing them on tissues known to express TESC positively and negatively. Browse below to find the TESC antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TESC Infographic by Boster Bio

All TESC Products

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Specificity

Applications

Price

TESC (NM_017899) Human Recombinant Protein

$813
Cat # PROTQ96BS2
20 µg

TESC (NM_017899) Human Over-expression Lysate

Human

$628
Cat # LS054997
100 µg

TESC Overview

Facts about Calcineurin B homologous protein 3.

TESC 3D structure. Source: alphafold

Calcineurin B homologous protein 3 (TESC)

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane.

Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.

Gene Information

Human
Gene Name:	TESC
Uniprot:	Q96BS2
Entrez:	54997

Family

Belongs to:

calcineurin regulatory subunit family

Alternative Names

calcineurin B homologous protein 3; CHP3; TSC

Molecular Weight

Mass (kDA):
24.75 kDA

Genomic Context


Human

Location:	12q24.22
Sequence:	12; NC_000012.12 (117038923..117099490, complement)

Tissue Specificity

Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta.

Subcellular Localizations

Nucleus. Cytoplasm. Membrane; Lipid-anchor. Cell membrane. Cell projection, lamellipodium. Cell projection, ruffle membrane. Colocalizes with SLC9A1 at the plasma membrane.