Telomere repeats-binding bouquet formation protein 2 (Terb2)

Meiosis-specific telomere-associated protein involved in meiotic telomere attachment into the nucleus inner membrane, a crucial measure for homologous pairing and synapsis. Part of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA into the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complicated.

During prophase, the complicated matures and promotes release of the shelterin/telosome complicated from telomeric DNA. .