TEC Antibodies

AND TEC ELISA kits, TEC Proteins

Many biological assays use antibodies to detect TEC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TEC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TEC antibodies...

We validate the specificity of these antibodies to TEC by testing them on tissues known to express TEC positively and negatively. Browse below to find the TEC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TEC Infographic by Boster Bio

All TEC Products

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Product

Figures

Specificity

Applications

Price

Anti-Tyrosine-protein kinase Tec Tec Antibody Picoband®

3 Q&As

Human, Rat

IHC, WB

$370
Cat # PA2000
100 μg/vial

Anti-Tec Antibody Picoband®

Human, Mouse, Rat

$370
Cat # A01031
100 μg/vial

Anti-Tyrosine-protein kinase Tec Tec Monoclonal Antibody

Human

ELISA, WB

$380
Cat # M01031
100ul

TEC (NM_003215) Human Over-expression Lysate

Human

$628
Cat # LS007006
100 µg

TEC Overview

Facts about Tyrosine-protein kinase Tec.

TEC 3D structure. Source: alphafold

Tyrosine-protein kinase Tec (TEC)

Non-receptor tyrosine kinase that leads to signaling from many receptors and participates as a signal transducer in several downstream pathways, such as regulation of the actin cytoskeleton. Plays a redundant part to ITK in regulation of the adaptive immune reaction.

Regulates the development, function and differentiation of traditional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction.

Gene Information

Human
Gene Name:	TEC
Uniprot:	P42680
Entrez:	7006

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.10; EC 2.7.10.2; MGC126760; MGC126762; PSCTK4; PSCTK4tyrosine-protein kinase Tec; tec protein tyrosine kinase; Tec

Molecular Weight

Mass (kDA):
73.581 kDA

Genomic Context


Human

Location:	4p12-p11
Sequence:	4; NC_000004.12 (48135783..48269864, complement)

Tissue Specificity

Expressed in a wide range of cells, including hematopoietic cell lines like myeloid, B-, and T-cell lineages.

Subcellular Localizations

Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Following B-cell or T-cell receptors activation by antigen, translocates to the plasma membrane through its PH domain. Thrombin and integrin engagement induces translocation of TEC to the cytoskeleton during platelet activation. In cardiac myocytes, assumes a diffuse intracellular localization under basal conditions but is recruited to striated structures upon various stimuli, including ATP (By similarity).