TDRD7 Antibodies

AND TDRD7 ELISA kits, TDRD7 Proteins

Many biological assays use antibodies to detect TDRD7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TDRD7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TDRD7 antibodies...

We validate the specificity of these antibodies to TDRD7 by testing them on tissues known to express TDRD7 positively and negatively. Browse below to find the TDRD7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TDRD7 Infographic by Boster Bio

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TDRD7 (NM_014290) Human Over-expression Lysate

Human

$628
Cat # LS023424
100 µg

TDRD7 Overview

Facts about Tudor domain-containing protein 7.

TDRD7 3D structure. Source: alphafold

Tudor domain-containing protein 7 (TDRD7)

Component of certain cytoplasmic RNA granules involved with post-transcriptional regulation of certain genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes like CRYBB3 and HSPB1 in the developing lens.

Also required during spermatogenesis. .

Gene Information

Human
Gene Name:	TDRD7
Uniprot:	Q8NHU6
Entrez:	23424

Family

Belongs to:

TDRD7 family

Alternative Names

KIAA1529; PCTAIRE2-binding protein; PCTAIRE2BPTRAP; RP11-508D10.1; Trap; tudor domain containing 7; tudor domain-containing protein 7; Tudor repeat associator with PCTAIRE 2

Molecular Weight

Mass (kDA):
123.586 kDA

Genomic Context


Human

Location:	9q22.33
Sequence:	9; NC_000009.12 (97412096..97496125)

Subcellular Localizations

Cytoplasm. Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity).

Diseases

Cataract
Glaucoma
Sterility
Immunologic Deficiency Syndromes
Multiple Myeloma
Malignant Neoplasms
Neoplasms
Hypospadias

Senile Cataract
Malignant Paraganglionic Neoplasm

Interacting Proteins

CDKN2A
GABPB1
TACC1

Pathways

Localization
Translation
Cell Development
Spermatogenesis
Germ Cell Development
Meiosis
Transport
Cell Migration
Mitosis
Spermatid Development

Regulation Of Gene Expression
Mrna Transport
Epiboly
Cell Differentiation
Oogenesis

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TDRD7

References

PMID: 10727952 by Hirose T., et al. Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain.

PMID: 20305267 by Callebaut I., et al. LOTUS, a new domain associated with small RNA pathways in the germline.