TDRD3 Antibodies

AND TDRD3 ELISA kits, TDRD3 Proteins

Many biological assays use antibodies to detect TDRD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TDRD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TDRD3 antibodies...

We validate the specificity of these antibodies to TDRD3 by testing them on tissues known to express TDRD3 positively and negatively. Browse below to find the TDRD3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TDRD3 Infographic by Boster Bio

All TDRD3 Products

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Product

Figures

Specificity

Applications

Price

Anti-TDRD3 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # A08978
100 μg/vial

TDRD3 (NM_030794) Human Over-expression Lysate

Human

$628
Cat # LS081550
100 µg

TDRD3 Overview

Facts about Tudor domain-containing protein 3.

TDRD3 3D structure. Source: alphafold

Tudor domain-containing protein 3 (TDRD3)

Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails correlated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins in these arginine- methylated loci.

In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. .

Gene Information

Human
Gene Name:	TDRD3
Uniprot:	Q9H7E2
Entrez:	81550

Family

Belongs to:

No superfamily

Alternative Names

FLJ21007; tudor domain containing 3; tudor domain-containing protein 3

Molecular Weight

Mass (kDA):
73.185 kDA

Genomic Context


Human

Location:	13q21.2
Sequence:	13; NC_000013.11 (60396457..60573879)

Tissue Specificity

Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Cytoplasm. Nucleus. Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules.

Diseases

Malignant Neoplasms
Fragile X Syndrome
Muscular Atrophy
Atrophy
Spinal Muscular Atrophy
Congenital Absence Of Germinal Epithelium Of Testes

Interacting Proteins

POLR2A
TOP3B

Pathways

Methylation
Pathogenesis
Localization

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TDRD3

References

PMID: 18632687 by Goulet I., et al. TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.

PMID: 15955813 by Cote J., et al. Tudor domains bind symmetrical dimethylated arginines.