TDP1 Antibodies

AND TDP1 ELISA kits, TDP1 Proteins

Many biological assays use antibodies to detect TDP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TDP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TDP1 antibodies...

We validate the specificity of these antibodies to TDP1 by testing them on tissues known to express TDP1 positively and negatively. Browse below to find the TDP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TDP1 Infographic by Boster Bio

All TDP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TDP1 Antibody

Human, Rat

IF, ICC, WB

$405
Cat # A02231
100ul

TDP1 (NM_001008744) Human Recombinant Protein

$813
Cat # PROTQ9NUW8
20 µg

Anti-TDP1 Mouse Monoclonal Antibody [Clone ID: OTI4H1]

Human

$523
Cat # M02231
100 µl

TDP1 (NM_001008744) Human Over-expression Lysate

Human

$628
Cat # LS055775
100 µg

TDP1 Overview

Facts about Tyrosyl-DNA phosphodiesterase 1.

TDP1 3D structure. Source: alphafold

Tyrosyl-DNA phosphodiesterase 1 (TDP1)

DNA repair enzyme that can remove a variety of covalent adducts from DNA via hydrolysis of a 3'-phosphodiester bond, giving rise to DNA using a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue.

Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand fractures due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA.

Gene Information

Human
Gene Name:	TDP1
Uniprot:	Q9NUW8
Entrez:	55775

Family

Belongs to:

tyrosyl-DNA phosphodiesterase family

Alternative Names

EC 3.1.4; EC 3.1.4.-; FLJ11090; MGC104252; SCAN1; Tyr-DNA phosphodiesterase 1; tyrosyl-DNA phosphodiesterase 1

Molecular Weight

Mass (kDA):
68.42 kDA

Genomic Context


Human

Location:	14q32.11
Sequence:	14; NC_000014.9 (89954923..90044768)

Tissue Specificity

Ubiquitously expressed. Similar expression throughout the central nervous system (whole brain, amygdala, caudate nucleus, cerebellum, cerebral cortex, frontal lobe, hippocampus, medulla oblongata, occipital lobe, putamen, substantia nigra, temporal lobe, thalamus, nucleus accumbens and spinal cord) and increased expression in testis and thymus.