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- Table of Contents
, No Gclids
TCP1 Antibodies
AND TCP1 ELISA kits, TCP1 Proteins
Many biological assays use antibodies to detect TCP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TCP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TCP1 antibodies...
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TCP1 Infographic by Boster Bio
All TCP1 Products
Product
Figures
Specificity
Applications
Price
Anti-TCP1 alpha Antibody Picoband®
1 Citations 1 Q&As
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9826
100 μg/vial
Cat # PB9826
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02389
100 μg/vial
Cat # M02389
100 μg/vial
Human
Flow Cytometry
$515
Cat # M02389-Dyl488
100 μg/vial
Cat # M02389-Dyl488
100 μg/vial
Human
Flow Cytometry
$515
Cat # M02389-Dyl550
100 μg/vial
Cat # M02389-Dyl550
100 μg/vial
TCP1 Overview
Facts about T-complex protein 1 subunit alpha.
T-complex protein 1 subunit alpha (TCP1)
Part of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transfers vesicles into the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | TCP1 |
| Uniprot: | P17987 |
| Entrez: | 6950 |
Family
| Belongs to: |
|---|
| TCP-1 chaperonin family |
Alternative Names
CCT1T-complex protein 1 subunit alpha; CCTa; CCT-alpha; D6S230E; tailless complex polypeptide 1; t-complex 1; T-complex protein 1, alpha subunit; TCP-1-alpha
Molecular Weight
Mass (kDA):
60.344 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.3 |
| Sequence: | 6; NC_000006.12 (159778498..159789703, complement) |
Subcellular Localizations
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Diseases
- Malignant Neoplasms
- Neoplasms
- Growth Arrest
- Carcinoma
- Adenocarcinoma
- Colorectal Cancer
- Schizophrenia
- Colorectal Neoplasms
- Inflammation
- Lung Neoplasms
- Ataxia
- Persistant Generalized Lymphadenopathy
- Hepatitis
Interacting Proteins
- CBFA2T2
- CCT2
- CCT4
- CCT8
- GBA
- OLR1
Pathways
- Cell Cycle
- Protein Folding
- Localization
- Translation
- Cell Death
- Cell Growth
- Transport
- Spermatogenesis
- Cell Cycle Arrest
- Cell Division
- Cell Proliferation
- Pathogenesis
- Chromosome Segregation
PTMs
- Phosphorylation
- Cleavage
- Acetylation
Research Areas
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TCP1
bosterbio.com/bosterbio-gene-info-cards/TCP1
References
PMID: 2377466 by Kirchhoff C., et al. Nucleotide and amino-acid sequence of human testis-derived TCP1.
PMID: 3653076 by Willison K., et al. The human homologue of the mouse T-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region.
1 Publications of Boster TCP1 Antibodies & ELISA Kits
- PubMed ID: 16403237, Inhaled nitric oxide alleviates hyperoxia suppressed phosphatidylcholine synthes...
*More publications can be found for each product on its corresponding product page