Tcf7l1 Antibodies

AND Tcf7l1 ELISA kits, Tcf7l1 Proteins

Many biological assays use antibodies to detect Tcf7l1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tcf7l1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tcf7l1 antibodies...

We validate the specificity of these antibodies to Tcf7l1 by testing them on tissues known to express Tcf7l1 positively and negatively. Browse below to find the Tcf7l1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Tcf7l1 Infographic by Boster Bio

All Tcf7l1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TCF7L1 Antibody Picoband®

1 Q&As

Human

IHC, WB

$370
Cat # PB9897
100 μg/vial

Anti-TCF3 TCF7L1 Rabbit Monoclonal Antibody

3 Q&As

Human

Flow Cytometry, WB

$370
Cat # M05152
100 μl

Anti-TCF-3 TCF7L1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05152
100ul

Tcf7l1 Overview

Facts about Transcription factor 7-like 1.

Transcription factor 7-like 1 (Tcf7l1)

Participates in the Wnt signaling pathway.
Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence.

Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the skin. .

Gene Information

Mouse
Gene Name:	Tcf7l1
Uniprot:	Q9Z1J1
Entrez:	21415

Family

Belongs to:

TCF/LEF family

Alternative Names

HMG box transcription factor 3; TCF3; TCF-3; TCF7L1; transcription factor 7-like 1 (T-cell specific, HMG-box); transcription factor 7-like 1

Molecular Weight

Mass (kDA):
62.298 kDA

Genomic Context


Mouse

Location:	6 C1\|6 32.27 cM
Sequence:	6;

Tissue Specificity

Detected in the basal layer of epidermis and in outer root sheath and bulge of hair follicles.

Diseases

Lymphohistiocytosis, Hemophagocytic
Leukemia
Neoplasms
Malignant Neoplasms
Acute Lymphocytic Leukemia
Cell Transformation, Neoplastic
Chromosomal Translocation
Nervousness
Carcinoma
Lymphoma
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Diabetes Mellitus
Malignant Paraganglionic Neoplasm

Insulinoma
Adult T-cell Lymphoma/leukemia
Malignant Tumor Of Colon
Tumor Progression
Cell Invasion
Neuroblastoma
Leukemogenesis

Pathways

Cell Differentiation
Cell Development
Cell Cycle
Cell Proliferation
Localization
Neurogenesis
Aging
B Cell Differentiation
V(d)j Recombination
Senescence
Cell Growth
Methylation
Lymphocyte Differentiation

Cell Division
Axis Specification
Angiogenesis
Regeneration
Cell Cycle Arrest
Cell Death
T Cell Differentiation

PTMs

Phosphorylation
Methylation
Cleavage
Acetylation

Ubiquitination
Demethylation
Phosphorothioation
Ubiquitinylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tcf7l1

References

PMID: 9488439 by Korinek V., et al. Two members of the Tcf family implicated in Wnt/b-catenin signaling during embryogenesis in the mouse.

PMID: 10498690 by DasGupta R., et al. Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation.