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- Table of Contents
Facts about Transcription factor 25.
Has been shown to repress transcription of SRF in vitro and so may play a role in heart development. .
Human | |
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Gene Name: | TCF25 |
Uniprot: | Q9BQ70 |
Entrez: | 22980 |
Belongs to: |
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TCF25 family |
hKIAA1049; KIAA1049Hulp1; Nuclear localized protein 1; Nulp1; NULP1PRO2620; TCF-25; transcription factor 25 (basic helix-loop-helix); transcription factor 25
Mass (kDA):
76.667 kDA
Human | |
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Location: | 16q24.3 |
Sequence: | 16; NC_000016.10 (89873592..89911384) |
In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.
Nucleus. Some staining in the cytosol.
PMID: 16574069 by Cai Z., et al. hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor.
PMID: 18068114 by Steen H., et al. Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein.