TATA-box-binding protein Antibodies

TATA-box-binding protein (TBP)

General transcription factor that functions at the heart of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682).

Part of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071). Part of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complicated ) through RNA polymerase I-dependent transcription (PubMed:15970593).

Gene Information

Human
Gene Name:	TBP
Uniprot:	P20226
Entrez:	6908

Family

Belongs to:
TBP family

Alternative Names

GTF2D; GTF2D1; HDL4; MGC126054; MGC126055; SCA17; TATA box binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box binding protein N-terminal domain; TATA-box factor; TATA-box-binding protein; TF2D; TFIIDMGC117320; Transcription initiation factor TFIID TBP subunit

Molecular Weight

Mass (kDA):
37.698 kDA

Genomic Context

Human
Location:	6q27
Sequence:	6; NC_000006.12 (170554333..170572870)

Tissue Specificity

Widely expressed, with levels highest in the testis and ovary.

Subcellular Localizations

Nucleus.

Diseases

• Neoplasms
• Malignant Neoplasms
• Ataxia
• Ataxia, Spinocerebellar
• Trinucleotide Repeat Expansion
• Carcinoma
• Neurodegenerative Disorders
• Punctate Inner Choroidopathy
• Hiv Infections
• Atrophy
• Retinoblastoma
• Huntington Disease

• Immunologic Deficiency Syndromes
• Malignant Paraganglionic Neoplasm
• Mammary Neoplasms
• Tuberculosis
• Leukemia
• Cytomegalovirus Infections
• Diabetes Mellitus

Interacting Proteins

• Cdx1
• GTF2A1
• GTF2A2
• GTF2B
• POU3F2

• SET
• TAF1
• TAF12
• TAF1A
• TAF1B

• TAF1C
• TP53

Pathways

• Cell Cycle
• Localization
• Cell Growth
• Transport
• Chromatin Remodeling
• Pathogenesis
• Cell Proliferation
• Regulation Of Gene Expression
• Reverse Transcription
• Methylation
• Dna Replication
• Cell Differentiation
• Translation

• Proteolysis
• Viral Transcription
• Mitosis
• Histone Acetylation
• Dna Repair
• Spermatogenesis
• Rrna Transcription

PTMs

• Phosphorylation
• Acetylation
• Cleavage
• Oxidation
• Methylation
• Reduction
• Dephosphorylation
• Nitration
• Carboxylation

• Bromination
• Hydroxylation
• Ubiquitination
• Deacetylation
• Sumoylation
• Biotinylation
• Farnesylation
• Glycosylation
• Demethylation

• Sulphation

Research Areas

• Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TBP

Boster Bio - Best Uses Of The TBP Marker

Are you interested in Boster bio and the TBP Marker Then you've come to the right spot in case. Here's the scoop about Boster Bio Anti–TAF1/Kat4 Antibody. This product is suitable for professional and amateur scientists. Scientists can utilize Boster's TBP Marker for a variety of samples. It can be used by all scientists from around the world.

Boster Bio Anti-TAF1/Kat4 Antibody

Boster Bio Anti-TAF1/Kat4 Antibody could be used to detect TAF1 in your samples. This reagent is priced according to the length of the immunogen and reacts with Human. Additionally you can keep the antibody at -20degC or at 4degC for up to a month. The antibody is made of synthetic peptides that are located at the carboxyl terminal of human TAF1. It is tested against both positive and negative samples to ensure stability over time.