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- Table of Contents
Facts about Tubulin-specific chaperone D.
Its ability to interact with beta tubulin is controlled via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2.
Human | |
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Gene Name: | TBCD |
Uniprot: | Q9BTW9 |
Entrez: | 6904 |
Belongs to: |
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TBCD family |
Beta-tubulin cofactor D; KIAA0988; SSD1; SSD-1; tfcD; tubulin folding cofactor D; Tubulin-folding cofactor D; tubulin-specific chaperone d
Mass (kDA):
132.6 kDA
Human | |
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Location: | 17q25.3 |
Sequence: | 17; NC_000017.11 (82752048..82945914) |
Ubiquitously expressed.
Cell junction, tight junction. Lateral cell membrane. Cytoplasm. Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localized in cell-cell contacts.
PMID: 11110777 by Schubert A., et al. Shear stress-dependent regulation of the human beta-tubulin folding cofactor D gene.
PMID: 10722852 by Martin L., et al. Tubulin folding cofactor D is a microtubule destabilizing protein.