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- Table of Contents
Facts about TBC1 domain family member 10A.
Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
.Human | |
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Gene Name: | TBC1D10A |
Uniprot: | Q9BXI6 |
Entrez: | 83874 |
Belongs to: |
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No superfamily |
EBP50-PDX interactor of 64 kDa; EPI64; rab27A-GAP-alpha; TBC1 domain family member 10A; TBC1 domain family, member 10A
Mass (kDA):
57.118 kDA
Human | |
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Location: | 22q12.2 |
Sequence: | 22; NC_000022.11 (30291990..30326941, complement) |
Cell projection, microvillus. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells.
PMID: 11285285 by Reczek D., et al. Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP.
PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.