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- Table of Contents
Facts about Tax1-binding protein 3.
Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway.
Human | |
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Gene Name: | TAX1BP3 |
Uniprot: | O14907 |
Entrez: | 30851 |
Belongs to: |
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No superfamily |
1G5; caM kinase-like vesicle-associated protein; CaM kinase-like vesicle-associated; MGC8407; VACAMKL; vesicle-associated calmodulin-binding protein
Mass (kDA):
13.735 kDA
Human | |
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Location: | 17p13.2 |
Sequence: | 17; NC_000017.11 (3662893..3668679, complement) |
Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes.
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the cell membrane by interaction with membrane proteins.
PMID: 9482110 by Rousset R., et al. The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.
PMID: 10673275 by Touchman J.W., et al. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.