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- Table of Contents
Facts about Taste receptor type 2 member 14.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). .
Human | |
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Gene Name: | TAS2R14 |
Uniprot: | Q9NYV8 |
Entrez: | 50840 |
Belongs to: |
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G-protein coupled receptor T2R family |
MGC125491; T2R14MGC125492; Taste receptor family B member 1; taste receptor, family B, member 1; taste receptor, type 2, member 14; TRB1taste receptor type 2 member 14
Mass (kDA):
36.16 kDA
Human | |
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Location: | 12p13.2 |
Sequence: | 12; NC_000012.12 (10938254..10939207, complement) |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed in testis (PubMed:16720576).
Membrane; Multi-pass membrane protein.
PMID: 10761934 by Adler E., et al. A novel family of mammalian taste receptors.
PMID: 15496549 by Fischer A., et al. Evolution of bitter taste receptors in humans and apes.