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- Table of Contents
Facts about Taste receptor type 2 member 1.
The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. .
Human | |
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Gene Name: | TAS2R1 |
Uniprot: | Q9NYW7 |
Entrez: | 50834 |
Belongs to: |
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G-protein coupled receptor T2R family |
MGC126778; T2R1MGC126780; Taste receptor family B member 7; taste receptor, family B, member 7; taste receptor, type 2, member 1; TRB7taste receptor type 2 member 1
Mass (kDA):
34.333 kDA
Human | |
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Location: | 5p15.31 |
Sequence: | 5; NC_000005.10 (9627347..9630351, complement) |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.
Membrane; Multi-pass membrane protein.
PMID: 10761934 by Adler E., et al. A novel family of mammalian taste receptors.
PMID: 15496549 by Fischer A., et al. Evolution of bitter taste receptors in humans and apes.