TARDBP Antibodies

AND TARDBP ELISA kits, TARDBP Proteins

Many biological assays use antibodies to detect TARDBP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TARDBP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TARDBP antibodies...

We validate the specificity of these antibodies to TARDBP by testing them on tissues known to express TARDBP positively and negatively. Browse below to find the TARDBP antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: CELA3B

TARDBP Infographic by Boster Bio

All TARDBP Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-TDP43 TARDBP Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M01001
100 μl

Anti-TDP43 TARDBP Monoclonal Antibody

1 Citations 6 Q&As

Bovine, Equine, Human, Mouse, Pig, Rat

IF, IHC, ICC, WB

$299
Cat # M01001-1
100ul

Anti-TDP43 TARDBP Antibody

1 Citations

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A01001
0.1 mg

Anti-TAR DNA-binding protein 43 TARDBP Antibody

1 Citations

Human, Mouse, Rat

IP, WB, RIP

$405
Cat # A01001-1
100ul

Anti-TDP43 TARDBP Antibody

1 Citations

Human, Mouse, Rat, Zebrafish

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A01001-2
100ul

Human TDP-43/TARDBP Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ13148
Starting from 4ug

Anti-TDP43 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01001-2
100 μl/vial

TDP43 (TARDBP) (NM_007375) Human Over-expression Lysate

Human

$628
Cat # LS023435
100 µg

Anti-TDP-43/TARDBP Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01001-3
100 µg/vial

TARDBP Overview

Facts about TAR DNA-binding protein 43.

TARDBP 3D structure. Source: alphafold

TAR DNA-binding protein 43 (TARDBP)

DNA and RNA-binding protein that regulates transcription and splicing. Involved in the regulation of CFTR splicing.

It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of the exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

Gene Information

Human
Gene Name:	TARDBP
Uniprot:	Q13148
Entrez:	23435

Family

Belongs to:

No superfamily

Alternative Names

ALS10; ALS10TAR DNA-binding protein-43; TAR DNA binding protein; TARDBP; TDP43; TDP-43; TDP-43TAR DNA-binding protein 43

Molecular Weight

Mass (kDA):
44.74 kDA

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (11012654..11030528)

Tissue Specificity

Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, Stress granule. Continuously travels in and out of the nucleus (PubMed:18957508). Localizes to stress granules in response to oxidative stress (PubMed:19765185).

Diseases

Amyotrophic Lateral Sclerosis
Sclerosis
Primary Lateral Sclerosis
Frontotemporal Lobar Degeneration
Feline Urological Syndrome
Dementia
Neurodegenerative Disorders
Nerve Degeneration
Frontotemporal Dementia
Motor Neuron Disease
Tdp-43 Proteinopathies
Sarcoma
Neuropathology Disease

Impaired Cognition
Secondary Parkinson Disease
Alzheimer's Disease
Weakness
Parkinson Disease
Nervousness
Liposarcoma

Interacting Proteins

ATXN2
IRAK2
PPP1R15A

Pathways

Pathogenesis
Rna Processing
Localization
Transport
Mrna Splicing
Translation
Cognition
Rna Splicing
Locomotion
Protein Folding
Cell Adhesion
Aging
Stress Granule Assembly

Embryo Development
Mitochondrial Fusion
Cell Division
Swimming
Rna Transport
Cytoplasmic Transport
Cell Proliferation

PTMs

Ubiquitination

Phosphorylation

Cleavage

Research Areas

Cell Cycle and Replication
Chromatin Research
DNA replication, Transcription, Translation and Splicing
Epigenetics
Immunology

Mitochondrial Fusion Proteins
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Transcription Factors and Regulators

Virology, Bacteria and Parasites

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TARDBP

References

PMID: 7745706 by Ou S.-H.I., et al. Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.

PMID: 17481916 by Strong M.J., et al. TDP43 is a human low molecular weight neurofilament (hNFL) mRNA- binding protein.

1 Publications of Boster TARDBP Antibodies & ELISA Kits

PubMed ID: 31452277, Zhang Y,Yang C,Yang S,Guo Z.MiRNA-27a decreases ultraviolet B irradiation-induce...

*More publications can be found for each product on its corresponding product page