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TACC1 Antibodies
AND TACC1 ELISA kits, TACC1 Proteins
Many biological assays use antibodies to detect TACC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TACC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TACC1 antibodies...
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TACC1 Infographic by Boster Bio
All TACC1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1648
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1648
1 kit, containing one 96-well plate and all necessary reagents
TACC1 Overview
Facts about Transforming acidic coiled-coil-containing protein 1.
Transforming acidic coiled-coil-containing protein 1 (TACC1)
Likely involved in the procedures that promote cell division before the formation of differentiated tissues. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TACC1 |
| Uniprot: | O75410 |
| Entrez: | 6867 |
Family
| Belongs to: |
|---|
| TACC family |
Alternative Names
DKFZp686K18126; FLJ42304; Ga55; Gastric cancer antigen Ga55; KIAA1103; taxin 1; taxin-1; transforming acidic coiled-coil-containing protein 1; transforming, acidic coiled-coil containing protein 1
Molecular Weight
Mass (kDA):
87.794 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p11.22 |
| Sequence: | 8; NC_000008.11 (38728205..38853028) |
Tissue Specificity
Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer.
Subcellular Localizations
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis.; [Isoform 5]: Membrane; Lipid-anchor.; [Isoform 10]: Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Mammary Neoplasms
- Carcinoma
- Ovarian Neoplasm
- Adenocarcinoma
- Multiple Myeloma
- Malignant Neoplasm Of Stomach
- Stomach Neoplasms
- Glioma
- Aneuploidy
Interacting Proteins
- AURKB
- BTRC
- CKAP5
- HTT
- LSM7
- MEMO1
- SH2D4A
- SNRPG
- STX5
- TDRD7
Pathways
- Cell Division
- Cell Cycle
- Cytokinesis
- Mitosis
- Localization
- Translation
- Cell Growth
- M Phase
- Anaphase
- Regulation Of Mitosis
- Oncogenesis
- Cell Proliferation
- Methylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TACC1
bosterbio.com/bosterbio-gene-info-cards/TACC1
References
PMID: 10435627 by Still I.H., et al. Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, from the 8p11 breast cancer amplicon.
PMID: 15207008 by Still I.H., et al. Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
1 Publications of Boster TACC1 Antibodies & ELISA Kits
- PubMed ID: -, Man-jing Jiang,Shuai Huang,Li Li et al.Rubus Suavissimus Alleviates High-fat Die...
*More publications can be found for each product on its corresponding product page