Synaptotagmin-3 (Syt3)

Ca(2+) sensor included in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.

Plays a role in dendrite formation by melanocytes. .