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Synaptotagmin-3 Antibodies
AND Syt3 ELISA kits, Synaptotagmin-3 Proteins
Many biological assays use antibodies to detect Synaptotagmin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptotagmin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptotagmin-3 antibodies...
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Syt3 Infographic by Boster Bio
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Syt3 Overview
Facts about Synaptotagmin-3.
Synaptotagmin-3 (Syt3)
Ca(2+) sensor included in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
Plays a role in dendrite formation by melanocytes. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Syt3 |
| Uniprot: | O35681 |
| Entrez: | 20981 |
Family
| Belongs to: |
|---|
| synaptotagmin family |
Alternative Names
synaptotagmin III; synaptotagmin-3; SytIII
Molecular Weight
Mass (kDA):
63.254 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7 B3|7 28.83 cM |
| Sequence: | 7; |
Diseases
- Nervousness
- Pituitary Diseases
- Cell Invasion
- Tetanus
- Insulinoma
- Exophthalmos
- Strabismus
- Esotropia
- Tissue Adhesions
Pathways
- Exocytosis
- Vesicle Fusion
- Secretion
- Localization
- Insulin Secretion
- Synaptic Vesicle Exocytosis
- Synaptic Vesicle Fusion
- Membrane Fusion
- Regulation Of Exocytosis
- Transport
- Cell Migration
PTMs
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Syt3
bosterbio.com/bosterbio-gene-info-cards/Syt3
References
PMID: 10531343 by Fukuda M., et al. Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.
PMID: 10531344 by Fukuda M., et al. A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.