Sepiapterin reductase Antibodies

AND SPR ELISA kits, Sepiapterin reductase Proteins

Many biological assays use antibodies to detect Sepiapterin reductase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sepiapterin reductase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sepiapterin reductase antibodies...

We validate the specificity of these antibodies to Sepiapterin reductase by testing them on tissues known to express SPR positively and negatively. Browse below to find the SPR antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPR Infographic by Boster Bio

All SPR Products

Product

Figures

Specificity

Applications

Price

Anti-SPR Antibody Picoband™

1 Citations 16 Q&As

Human, Mouse

ELISA, WB

$370
Cat # A00416-1
100 μg/vial

Anti-Sepiapterin reductase SPR Antibody

1 Citations

Human, Mouse, Rat

$405
Cat # A00416
100ul

Human Sepiapterin reductase Recombinant Protein

SDS-PAGE

$250
Cat # PROTP35270
Starting from 20ug

Mouse Spr Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ91XH5
Starting from 20ug

Anti-SPR Mouse Monoclonal Antibody [Clone ID: OTI2C6]

+13

Human, Monkey

Flow Cytometry, IF, IHC, WB

$523
Cat # M00416
100 µl

Anti-SPR Mouse Monoclonal Antibody [Clone ID: OTI4F5]

+11

Human, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M00416-1
100 µl

SPR (NM_003124) Human Over-expression Lysate

Human

$628
Cat # LS006697
100 µg

SPR Overview

Facts about Sepiapterin reductase.

SPR 3D structure. Source: alphafold

Sepiapterin reductase (SPR)

Catalyzes the last one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. .

Gene Information

Human
Gene Name:	SPR
Uniprot:	P35270
Entrez:	6697

Family

Belongs to:

sepiapterin reductase family

Alternative Names

EC 1.1.1.153; Gm10328; SDR38C1; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR

Molecular Weight

Mass (kDA):
28.048 kDA

Genomic Context


Human

Location:	2p13.2
Sequence:	2; NC_000002.12 (72887408..72892158)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Tissue Adhesions
Neoplasms
Malaria
Hiv Infections
Inflammation
Pain
Alzheimer's Disease
Diabetes Mellitus
Infective Disorder
Influenza
Carcinoma
Cerebral Palsy

Muscle Spasticity
Salmonella Infections
Malaria, Falciparum
Headache
Nervousness
Hepatitis
Hypertensive Disease

Pathways

Regeneration
Transport
Localization
Cell Adhesion
Immune Response
Coagulation
Cell Proliferation
Translation
Pathogenesis
Conjugation
Secretion
Glycosylation
Angiogenesis

Proteolysis
Cell Growth
Virulence
Reflex
Methylation
Blood Coagulation
Cell Cycle

PTMs

Biotinylation
Phosphorylation
Cleavage
Glycosylation
Methylation
Oxidation
Reduction
Carboxylation
Dephosphorylation
Amination

Nitration
Myristoylation
Sumoylation
Glutathionylation
Hydroxylation
Deamination
Amidation
Sulphation
Phosphorothioation
Bromination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPR

References

PMID: 1883349 by Ichinose H., et al. Cloning and sequencing of cDNA encoding human sepiapterin reductase -- an enzyme involved in tetrahydrobiopterin biosynthesis.

PMID: 8440319 by Maier J., et al. Detection of a novel sepiapterin reductase mRNA: assay of mRNA in various cells and tissues of various species.

1 Publications of Boster Sepiapterin reductase Antibodies & ELISA Kits

PubMed ID: 24596465, Alterations in the endometrium of rats, rabbits, and?Macaca mulatta?that receive...

*More publications can be found for each product on its corresponding product page