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- Table of Contents
, No Gclids
Spindoc Antibodies
AND Spindoc ELISA kits, Spindoc Proteins
Many biological assays use antibodies to detect Spindoc, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spindoc in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spindoc antibodies...
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Spindoc Infographic by Boster Bio
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Spindoc Overview
Facts about Spindlin interactor and repressor of chromatin-binding protein.
Spindlin interactor and repressor of chromatin-binding protein (Spindoc)
Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes as well as the SPIN1-mediated activation of the Wnt signaling pathway (PubMed:29061846).
Can also inhibit the histone methyl- binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Spindoc |
| Uniprot: | Q05AH6 |
| Entrez: | 68229 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Spindlin interactor and repressor of chromatin-binding protein
Molecular Weight
Mass (kDA):
41.245 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 19|19 A |
| Sequence: | 19; |
PTMs
- Isopeptide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Spindoc
bosterbio.com/bosterbio-gene-info-cards/Spindoc
References
PMID: 29061846 by Bae N., et al. A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1.