Smoothelin-like protein 1 Antibodies

AND Smtnl1 ELISA kits, Smoothelin-like protein 1 Proteins

Many biological assays use antibodies to detect Smoothelin-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smoothelin-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smoothelin-like protein 1 antibodies...

We validate the specificity of these antibodies to Smoothelin-like protein 1 by testing them on tissues known to express Smtnl1 positively and negatively. Browse below to find the Smtnl1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Smtnl1 Infographic by Boster Bio

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SMTNL1 (NM_001105565) Human Recombinant Protein

$813
Cat # PROTA8MU46
20 µg

Smtnl1 Overview

Facts about Smoothelin-like protein 1.

Smoothelin-like protein 1 (Smtnl1)

Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation.

Phosphorylation in Ser-301 reduces this inhibitory action. .

Gene Information

Mouse
Gene Name:	Smtnl1
Uniprot:	Q99LM3
Entrez:	68678

Family

Belongs to:

smoothelin family

Alternative Names

Smoothelin-like protein 1

Molecular Weight

Mass (kDA):
49.525 kDA

Genomic Context


Mouse

Location:	2\|2 D
Sequence:	2;

Tissue Specificity

Widely expressed, with highest expression in skeletal muscles (at protein level). Within striated muscles, significantly more expressed in soleus muscle compared with plantaris muscle or white vastus (at protein level). 30-40% lower expression in females than in males (at protein level). Expressed in type 2a fibers, but not detected in fast twitch type 2b muscle white vastus nor in oxidative type I/b heart muscle (at protein level). Expressed within myometrial cells of the uterus, as well as in the endometrial layer. In the aorta, confined to smooth muscle cells. Not detected in endothelial cells.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smtnl1

References

PMID: 15327999 by Borman M.A., et al. Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins.

PMID: 18310078 by Wooldridge A.A., et al. Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.