Slc9b2 Antibodies

AND Slc9b2 ELISA kits, Slc9b2 Proteins

Many biological assays use antibodies to detect Slc9b2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slc9b2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slc9b2 antibodies...

We validate the specificity of these antibodies to Slc9b2 by testing them on tissues known to express Slc9b2 positively and negatively. Browse below to find the Slc9b2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slc9b2 Overview

Facts about Sodium/hydrogen exchanger 9B2.

Sodium/hydrogen exchanger 9B2 (Slc9b2)

Na(+)/H(+) antiporter which extrudes Na(+) or Li(+) in exchange for outside protons across the membrane (PubMed:18508966, PubMed:17988971). Contributes to the regulation of intracellular pH, sodium homeostasis, and cell volume.

Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells (PubMed:23720317). Involved in sperm motility and fertility (PubMed:27010853).

Gene Information

Mouse
Gene Name:	Slc9b2
Uniprot:	Q5BKR2
Entrez:	97086

Family

Belongs to:

monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

Alternative Names

FLJ23984; Mitochondrial Na(+)/H(+) exchanger NHA2; mitochondrial sodium/hydrogen exchanger NHA2; Na(+)/H(+) exchanger-like domain-containing protein 2; Na+/H+ exchanger domain containing 2; NHA2; NHA2NHE10; NHE domain-containing protein 2; NHE10; NHEDC2; SLC9B2; Sodium/hydrogen exchanger-like domain-containing protein 2

Molecular Weight

Mass (kDA):
58.934 kDA

Genomic Context


Mouse

Location:	3\|3 G3
Sequence:	3;

Tissue Specificity

Widely expressed (PubMed:18000046, PubMed:18508966, PubMed:17988971). However expression seems to be restricted to specific cell types within individual organs, e.g. osteoclasts in the bone, distal tubules of the kidney or beta- cells of Langerhans islets (PubMed:18508966, PubMed:17988971, PubMed:17698421, PubMed:23720317). In sperm specifically present in the principal piece of sperm tail (at protein level) (PubMed:27010853).

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc9b2

References

PMID: 17698421 by Pham L., et al. Expression analysis of nha-oc/NHA2: a novel gene selectively expressed in osteoclasts.

PMID: 18000046 by Xiang M., et al. A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension.