Sodium/calcium exchanger 2 (SLC8A2)

Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and consequently contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells.

Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal stimulation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion.