This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about b(0,+)-type amino acid transporter 1.
.
Human | |
---|---|
Gene Name: | SLC7A9 |
Uniprot: | P82251 |
Entrez: | 11136 |
Belongs to: |
---|
amino acid-polyamine-organocation (APC) superfamily |
b(0,+)AT; b(0+)AT; B(0+)-type amino acid transporter 1; BAT1; bo+ amino acid transporter; CSNU3; FLJ94301; Glycoprotein-associated amino acid transporter b0+AT1; SLC7A9; solute carrier family 7 (cationic amino acid transporter, y+ system), member 9; Solute carrier family 7 member 9
Mass (kDA):
53.481 kDA
Human | |
---|---|
Location: | 19q13.11 |
Sequence: | 19; NC_000019.10 (32830511..32870957, complement) |
Expressed in the brush border membrane in the kidney (at protein level). Kidney, small intestine, liver and placenta.
Apical cell membrane; Multi-pass membrane protein.
Many biological assays use antibodies for SLC7A9. These can be monoclonal, polyclonal, or multiclonal. They can react with SLC7A9 in a variety animals. Boster Bio developed antibodies against this marker by using antibodies made from rabbit and mice. The antibody has many uses, including the detection of SLC7A9 for cancer and infectious disease.
SLC7A9 is an indicator found on the membranes many organisms. Biological assays detect this protein using antibodies. These antibodies can be monoclonal or multiclonal and react to SLC7A9 in a variety animal samples. Boster Bio's antibodies are developed using rabbit and mouse models organisms to ensure high specificity.
It is a common practice to create antibodies that detect SLC7A9 for biological assays. They are typically monoclonal or polyclonal and react with SLC7A9 in many animal samples. Boster Bio uses rabbit and mouse to test the effectiveness of antibodies. Boster Bio performed several studies with human serum, plasma, and other samples to evaluate the effectiveness.
The SLC7A9 gene is located on the chromosomes 14 and 16, and can be detected by a DNA diagnostic test. An acrylamide gel electrophoresis technique detects DNA. The letter C above the lane indicates the control band. Asterisks are bands that are specific to the mutated variant. You should provide detailed descriptions of each view. The marker may require directional information. The application page 5 lists all requirements.
In 1999, the International Cystinuria Consortium cloned the SLC7A9 genetic code. The SLC7A9 gene encodes a 487-amino acid protein known as bo,+AT. The SLC7A9 gene cotransfected bo,+AT and the SLC7A9 genes to identify the gene as a member the family of light amino acid transporters. The rBAT gene was then correctly localized in COS cell lines, which are fibroblast-like cells.
SLC7A9 may be associated with a variety diseases, including type A disease. Type AB patients can have no symptoms but could be affected by type B disease. Type B is defined by the presence two mutations (in SLC7A9) and coincidental carriage status for SLC3A1. A type B disease was diagnosed in one case. The patient had three mutations: a M467T mutation in SLC3A1 as well as two missense mutations SLC7A9.
Researchers who are studying the SLC7A9 genetic gene will find the best use of the gene to learn more about Steven Boster. Steve Boster, who was born on Sunday June 26, 2022, passed away. His COVID-19 gene is the locus for his sarcophagus. This gene is most commonly linked to cancer, but it has many other uses.
Steve loved his family more than anything. His singing was so powerful and low that he sang in private. He enjoyed sports, especially his favorite team, and auto racing. He attended the local racetrack every Friday night and would often attend extra events on weekends. This genetic marker is well-known for its ability to diagnose cancer and other genetic diseases.
PMID: 10471498 by Feliubadalo L., et al. Non-type I cystinuria caused by mutations in SLC7A9, encoding a subunit (b0,+AT) of rBAT.
PMID: 10588648 by Pfeiffer R., et al. Luminal heterodimeric amino acid transporter defective in cystinuria.