Slc36a1 Antibodies

AND Slc36a1 ELISA kits, Slc36a1 Proteins

Many biological assays use antibodies to detect Slc36a1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slc36a1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slc36a1 antibodies...

We validate the specificity of these antibodies to Slc36a1 by testing them on tissues known to express Slc36a1 positively and negatively. Browse below to find the Slc36a1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slc36a1 Infographic by Boster Bio

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SLC36A1 (NM_078483) Human Over-expression Lysate

Human

$960
Cat # LS206358
100 µg

Slc36a1 Overview

Facts about Proton-coupled amino acid transporter 1.

Proton-coupled amino acid transporter 1 (Slc36a1)

Neutral amino acid/proton symporter. Probably involved in the efflux of lysosomal proteolysis items like L-proline, L-alanine and glycine from the mobile.

May play a role in specifying sites for exocytosis in neurons. .

Gene Information

Rat
Gene Name:	Slc36a1
Uniprot:	Q924A5
Entrez:	155205

Family

Belongs to:

amino acid/polyamine transporter 2 family

Alternative Names

PAT1; solute carrier family 36 (proton/amino acid symporter), member 1

Molecular Weight

Mass (kDA):
52.569 kDA

Genomic Context


Rat

Location:	10q22
Sequence:	10;

Tissue Specificity

Widely expressed and predominantly expressed in brain. Within the brain, expression restricted to neurons and not detected in glial cells. Abundant in regions rich in neurons using glutamate and GABA such as Purkinje cells in the cerebellum and pyramidal cells in the hippocampus.

Diseases

Malignant Neoplasms
Neoplasms
Hypertensive Disease
Alzheimer's Disease
Inflammatory Bowel Diseases
Diarrhea
Bacterial Infections
Epilepsy
Nervousness
Hyperglycemia
Infective Disorder
Schizophrenia

Prion Diseases
Adenoma
Dyslipidemias
Hyperuricemia
Confusion
Malignant Tumor Of Colon
Infertility

Pathways

Transport
Intestinal Absorption
Symport
Amino Acid Transport
Transepithelial Transport
Drug Transport
Protein Digestion
Localization
Dipeptide Transport
Exocytosis
Pathogenesis
Secretion
Intracellular Transport

Cell Migration
Aging
Amino Acid Homeostasis
Endocytosis
Methylation
Membrane Depolarization
Translation

PTMs

Phosphorylation
Carboxylation

Biotinylation
Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc36a1

References

PMID: 11390972 by Sagne C., et al. Identification and characterization of a lysosomal transporter for small neutral amino acids.

PMID: 12598615 by Wreden C.C., et al. The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons.