SLC25A12 Antibodies

AND SLC25A12 ELISA kits, SLC25A12 Proteins

Many biological assays use antibodies to detect SLC25A12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC25A12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC25A12 antibodies...

We validate the specificity of these antibodies to SLC25A12 by testing them on tissues known to express SLC25A12 positively and negatively. Browse below to find the SLC25A12 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC25A12 Infographic by Boster Bio

All SLC25A12 Products

Product

Figures

Specificity

Applications

Price

Anti-ARALAR SLC25A12 Antibody

13 Q&As

Human

$399
Cat # A04746
100μl

Anti-SLC25A12 Antibody

Human, Rat

IHC, WB

$405
Cat # A04746-1
100ul

Anti-SLC25A12 Antibody

Human, Mouse, Rat

$405
Cat # A04746-2
100ul

Anti-SLC25A12 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M04746
100 μl/vial

SLC25A12 (NM_003705) Human Over-expression Lysate

Human

$628
Cat # LS008604
100 µg

SLC25A12 Overview

Facts about Calcium-binding mitochondrial carrier protein Aralar1.

SLC25A12 3D structure. Source: alphafold

Calcium-binding mitochondrial carrier protein Aralar1 (SLC25A12)

Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane (PubMed:11566871, PubMed:25410934). May have a function in the urea cycle (PubMed:11566871).

Gene Information

Human
Gene Name:	SLC25A12
Uniprot:	O75746
Entrez:	8604

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

AGC1; araceli hiperlarga; ARALAR; ARALAR1; calcium binding mitochondrial carrier superfamily member Aralar1; calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; solute carrier family 25 (mitochondrial carrier, Aralar), member 12; Solute carrier family 25 member 12

Molecular Weight

Mass (kDA):
74.762 kDA

Genomic Context


Human

Location:	2q31.1
Sequence:	2; NC_000002.12 (171783405..171894306, complement)

Tissue Specificity

Expressed predominantly in the heart and skeletal muscle, weakly in brain and kidney.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Autistic Disorder
Autism Spectrum Disorders
Dysequilibrium Syndrome
Citrullinemia
Nervousness
Child Development Disorders, Pervasive
Epilepsy
Developmental Disabilities
Neonatal Hepatitis
Mitochondrial Diseases

Insulin Resistance
Mohr-tranebjaerg Syndrome
Speech Delay
Encephalitis
Psychomotor Disorders

Pathways

Transport
Insulin Secretion
Localization
Malate-aspartate Shuttle
Secretion
Oxidative Phosphorylation
Myelination
Urea Cycle
Pathogenesis
Membrane Hyperpolarization
Brain Development

Cell Differentiation
Protein Import
Exocytosis
Fatty Acid Oxidation
Glycolysis

PTMs

Oxidation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A12

References

PMID: 9722566 by Del Arco A., et al. Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain.

PMID: 11566871 by Palmieri L., et al. Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria.