Slc17a8 Antibodies

AND Slc17a8 ELISA kits, Slc17a8 Proteins

Many biological assays use antibodies to detect Slc17a8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slc17a8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slc17a8 antibodies...

We validate the specificity of these antibodies to Slc17a8 by testing them on tissues known to express Slc17a8 positively and negatively. Browse below to find the Slc17a8 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slc17a8 Overview

Facts about Vesicular glutamate transporter 3.

Vesicular glutamate transporter 3 (Slc17a8)

Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.

Gene Information

Mouse
Gene Name:	Slc17a8
Uniprot:	Q8BFU8
Entrez:	216227

Family

Belongs to:

major facilitator superfamily

Alternative Names

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

Molecular Weight

Mass (kDA):
66.148 kDA

Genomic Context


Mouse

Location:	10\|10 C2
Sequence:	10;

Tissue Specificity

Expressed in restricted areas of the brain. Highest expression is found in the neurons of the basal forebrain, the hippocampal formation, and the majority of the neurons of the mesencephalic raphe nuclei. Expressed in inner hair cells of the ear.

Diseases

Nervousness
Varicosity
Catalepsy
Complete Hearing Loss
Disease Of Adrenal Medulla
Nerve Damage
Amyotrophic Lateral Sclerosis
Diabetes Mellitus
Pituitary Diseases

Pain
Sensorineural Hearing Loss (disorder)
Inflammation
Presbycusis

Pathways

Transport
Exocytosis
Localization
Synaptic Transmission
Acetylcholine Uptake
Cellular Localization
Aging
Brain Development

Hypersensitivity
Blood Circulation
Innervation

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc17a8

References

PMID: 12384506 by Schaefer M.K.-H., et al. Molecular cloning and functional identification of mouse vesicular glutamate transporter 3 and its expression in subsets of novel excitatory neurons.

PMID: 18674745 by Ruel J., et al. Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice.