Endophilin-A2 Antibodies

AND SH3GL1 ELISA kits, Endophilin-A2 Proteins

Many biological assays use antibodies to detect Endophilin-A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endophilin-A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endophilin-A2 antibodies...

We validate the specificity of these antibodies to Endophilin-A2 by testing them on tissues known to express SH3GL1 positively and negatively. Browse below to find the SH3GL1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH3GL1 Infographic by Boster Bio

All SH3GL1 Products

Product

Figures

Specificity

Applications

Price

Anti-Endophilin-A2 SH3GL1 Antibody

Human, Monkey, Mouse, Rat

IHC, WB

$405
Cat # A05946
100ul

SH3 containing Grb 2 like 1 protein (SH3GL1) (NM_003025) Human Recombinant Protein

$1249
Cat # PROTQ99961
20 µg

Anti-SH3 containing Grb 2 like 1 protein (SH3GL1) Mouse Monoclonal Antibody [Clone ID: OTI2F5]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M05946
100 µl

SH3 containing Grb 2 like 1 protein (SH3GL1) (NM_003025) Human Over-expression Lysate

Human

$628
Cat # LS006455
100 µg

SH3GL1 Overview

Facts about Endophilin-A2.

SH3GL1 3D structure. Source: alphafold

Endophilin-A2 (SH3GL1)

Implicated in endocytosis.
May recruit other proteins to membranes with higher curvature (By similarity).

. .

Gene Information

Human
Gene Name:	SH3GL1
Uniprot:	Q99961
Entrez:	6455

Family

Belongs to:

endophilin family

Alternative Names

CNSA1endophilin-2; EEN fusion partner of MLL; EENSH3 domain-containing GRB2-like protein 1; Endophilin-2; extra 11-19 leukemia fusion; Extra eleven-nineteen leukemia fusion gene protein; MGC111371; SH3 domain protein 2B; SH3-containing Grb-2-like 1 protein; SH3D2Bendophilin-A2; SH3-domain GRB2-like 1; SH3P8

Molecular Weight

Mass (kDA):
41.49 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (4360369..4400547, complement)

Tissue Specificity

Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.

Subcellular Localizations

Cytoplasm. Early endosome membrane; Peripheral membrane protein. Cell projection, podosome. Associated with postsynaptic endosomes in hippocampal neurons.

Diseases

Leukemia
Leukemia, Myelocytic, Acute
Cell Transformation, Neoplastic
Myeloid Leukemia
Leukemogenesis
Chromosomal Translocation
Ataxia
Scoliosis, Unspecified
Acute Leukemia
Neurodegenerative Disorders
Trinucleotide Repeat Expansion
Adolescent Idiopathic Scoliosis

Nystagmus
Neoplasm Invasiveness
Animal Mammary Neoplasms
Dyskinetic Syndrome
Malignant Neoplasms
Neoplasms

Interacting Proteins

DPPA4
GPKOW
LRRK2
SH2D4A
SH3GL2

SH3GL3

Pathways

Endocytosis
Cell Proliferation
Localization
Pathogenesis
Clathrin-mediated Endocytosis
Glycosylation
Metaphase
Anaphase
Glomerular Filtration

Actin Filament Organization
Telophase
Cell Cycle
Regulation Of Cell Proliferation

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH3GL1

References

PMID: 9169142 by Giachino C., et al. A novel SH3-containing human gene family preferentially expressed in the central nervous system.

PMID: 9122235 by So C.W., et al. EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia.