Setd7 Antibodies

AND Setd7 ELISA kits, Setd7 Proteins

Many biological assays use antibodies to detect Setd7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Setd7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Setd7 antibodies...

We validate the specificity of these antibodies to Setd7 by testing them on tissues known to express Setd7 positively and negatively. Browse below to find the Setd7 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Setd7 Infographic by Boster Bio

All Setd7 Products

Product

Figures

Specificity

Applications

Price

Anti-SETD7/Set7 Rabbit Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

IP, WB

$370
Cat # M02793
100 μl

Human SET7/9 Recombinant Protein

SDS-PAGE

$234
Cat # PROTQ8WTS6
Starting from 20ug

Anti-SETD7 Mouse Monoclonal Antibody [Clone ID: OTI2D10]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M02793-1
100 µl

SETD7 (NM_030648) Human Over-expression Lysate

Human

$628
Cat # LS080854
100 µg

Setd7 Overview

Facts about Histone-lysine N-methyltransferase SETD7.

Histone-lysine N-methyltransferase SETD7 (Setd7)

Histone methyltransferase that especially monomethylates'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription.

Gene Information

Mouse
Gene Name:	Setd7
Uniprot:	Q8VHL1
Entrez:	73251

Family

Belongs to:

class V-like SAM-binding methyltransferase superfamily

Alternative Names

EC 2.1.1.43; H3-K4-HMTase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; KIAA1717SET domain-containing protein 7; KMT7FLJ21193; Lysine N-methyltransferase 7; SET domain containing (lysine methyltransferase) 7; SET7/9Histone H3-K4 methyltransferase SETD7; SET7Set9; SET9

Molecular Weight

Mass (kDA):
40.506 kDA

Genomic Context


Mouse

Location:	3\|3 C
Sequence:	3;

Diseases

Neoplasms
Malignant Neoplasms
Diabetes Mellitus
Hyperglycemia
Diabetic Angiopathies
Inflammation
Genotoxic Stress
Leukemia
Complications Of Diabetes Mellitus
Carcinogenesis
Autoimmune Reaction
Oncogene Activation Process
Diabetic Nephropathy

Myeloid Leukemia
Pituitary Diseases
Aplastic Anemia
Ulnar-mammary Syndrome Of Pallister
Mammary Neoplasms
Retinal Diseases
Premenstrual Tension

Pathways

Methylation
Cell Cycle
Histone Methylation
Chromatin Remodeling
Histone Modification
Localization
Demethylation
Cell Death
Gene Silencing
Histone Acetylation
Mitosis
Dna Methylation
Pathogenesis

Atp-dependent Chromatin Remodeling
Aging
Dna Demethylation
M Phase
Cell Cycle Arrest
Cytokinesis
Inflammatory Response

PTMs

Methylation
Acetylation
Phosphorylation

Demethylation
Biotinylation
Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Setd7

References

PMID: 11779497 by Wang H., et al. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

PMID: 12711597 by Chakrabarti S.K., et al. Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells.